This book provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations.
* Contributions from leading international authorities in the field
* Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system
* Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator
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An up-to-date insight into the mechanism of action of modern immunopotoentiators and their potential use in future vaccinesFrom the Back Cover:
Immunopotentiators in Modern Vaccines is an in-depth exploration of the current, most promising approaches to vaccine adjuvants. The book extends from examples of pre-clinical research all the way through to clinical evaluation, providing a thorough examination of the mechanisms which govern the activity of vaccine adjuvants and delivery systems. Wherever possible, a detailed description is provided to show how each adjuvant achieves its effects, highlighting opportunities for improving the design of adjuvants in the future.
* Immunopotentiators classified by function
* Exceptional illustrations depicting immunological pathways and the impact of adjuvants on cellular and molecular interactions
* US FDA perspectives highlight how future adjuvants will be approved for new generation vaccines
This book is intended for professionals and academics working in vaccinology who want up-to-date information about the mechanisms of modern immunopotentiators and their potential use in future rational vaccine design. It will also be an invaluable resource for decision makers and researchers in the field of vaccinology, policy makers, registration officers, marketing managers and students in the biomedical field.
Immunopotentiators in Modern Vaccines is edited by Virgil E.J.C. Schijns, (Professor, Dr, PhD) Head of Vaccine Technology and Immunology R&D Intervet Int. B.V. and Principal Immunologist, Nobilon Akzonobel, The Netherlands and part-time Professor in Immunology and Virology, Department of Population Health and Pathbiology, NC State University, Raleigh, USA; Derek T O’Hagan, (B.pharm, MR Pharm Soc GB, PhD) Senior Director and Head of Vaccine Delivery Research, Chiron Vaccines, Emeryville, USA.
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