From the Back Cover:
Nonviral vectors are commonly used in human gene therapy trials around the world. Compared to viral vectors, they are safer, more convenient, and less expensive to produce. This book is the first to focus entirely on the nonviral vector.
Nonviral Vectors for Gene Therapy covers historical aspects, structure and function, and preclinical and clinical applications of several established nonviral vectors, including cationic liposomes, polymers and peptides, gene gun, and naked DNA. New vectors such as LPD and nanoparticles are also described. This book is a must-read for anyone interested in gene therapy or its potential impact in medicine and biology.
Key Features:
* Presents state-of-the-art developments of nonviral vectors as tools for modern molecular medicine
* Covers all types of nonviral vectors, from molecular structure to therapeutic application
* Includes a comprehensive review of synthetic vectors
* Provides contributions from the major investigators and leading experts in the field
Review:
"...Chapters are written by leading experts and recognized authorities in the field, and the editors have done a remarkable job of ensuring that the level of presentation remains constant throughout... The book is well illustrated, and includes several pages of color plates and a functional index... This volume is a succinct, readable introduction to the development and use of nonviral vectors in gene therapy, and should serve to stimulate further research into this field. Its appeal, however, is not limited to those working in gene therapy. It should also be read by molecular biologists and especially cell biologists, whose work on basic cellular mechanisms of uptake and transport are needed to further an understanding of how to design effective vectors for gene therapy."
--DOODY'S PUBLISHING REVIEWS (2000)
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