Mechanisms of Memory - Hardcover

Sweatt, J. David

Hardcover

ISBN 10: 0123749514 ISBN 13: 9780123749512

Publisher: Academic Press, 2009

Synopsis

This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding.

• More than 25% new content, particularly expanding the scope to include new findings in translational research.
• Unique in its depth of coverage of molecular and cellular mechanisms
• Extensive cross-referencing to Comprehensive Learning and Memory
• Discusses clinically relevant memory disorders in the context of modern molecular research and includes numerous practical examples

About this title

Book Description:

Provides an overview of the cellular and molecular mechanisms involved in learning and memory.

From the Back Cover:

Mechanisms of Memory, second edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology to the molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, such as mental retardation syndromes and Alzheimer’s Disease. Written in a readable and engaging style, the book emphasizes results from the cutting edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics, and molecular structure.

The book draws numerous examples from the recent experimental literature, and has as a unifying theme the modern hypothesis-testing approach to basic research. As such, the book provides a foundation of experimental design that should be useful to all students pursuing an interest in laboratory research. In addition, active researchers in the learning and memory field will benefit from its extensive review of recent publications in the area, cross-references to detailed recent reviews, and from the cross-disciplinary approach used in writing the book.

• Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design
• Extensively illustrated throughout with many new, full color figures and photographs to help explain key concepts
• Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008)
• A companion website provides figures in PowerPoint format plus additional, detailed further reading references

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Mechanisms of Memory, second edition, is the only available comprehensive overview of the cellular and molecular mechanisms underlying higher-order learning and memory. Focusing on mechanisms relevant to hippocampus-dependent memory formation, the book progresses systematically from behavior to cellular physiology to the molecular and genetic levels. Moreover, it integrates modern discoveries concerning learning and memory disorders, such as mental retardation syndromes and Alzheimer’s Disease. Written in a readable and engaging style, the book emphasizes results from the cutting edge of contemporary methodologies, such as genetic engineering, molecular biology, complex behavioral characterization, cellular physiology, epigenetics, and molecular structure.

The book draws numerous examples from the recent experimental literature, and has as a unifying theme the modern hypothesis-testing approach to basic research. As such, the book provides a foundation of experimental design that should be useful to all students pursuing an interest in laboratory research. In addition, active researchers in the learning and memory field will benefit from its extensive review of recent publications in the area, cross-references to detailed recent reviews, and from the cross-disciplinary approach used in writing the book.

• Five new chapters cover human learning and memory, the molecular and cellular basis of associative learning, Aplysia non-associative learning, the NMDA receptor, and experimental design
• Extensively illustrated throughout with many new, full color figures and photographs to help explain key concepts
• Each chapter includes suggested readings for journal clubs, more introductory material for students, extensive cross-referencing to detailed, current reviews in Learning and Memory: A Comprehensive Reference (Academic Press, 2008)
• A companion website provides figures in PowerPoint format plus additional, detailed further reading references

About this edition

• Publisher: Academic Press
• Publication date: 2009
• ISBN 10: 0123749514
• ISBN 13: 9780123749512
• Binding: Hardcover
• Edition number: 2
• Number of pages: 362