The study of G-quadruplexes has emerged in recent years as an important focus of research in nucleic acids. This is now a rapidly growing area, not least because of its potential as a novel approach to cancer therapeutics, and there is much current activity on the design of quadruplex-selective small-molecule ligands and the study of their cellular effects. This timely publication gives a uniquely integrated view of quadruplex nucleic acids that will be a major resource in future drug-discovery strategies.
Therapeutic Applications of Quadruplex Nucleic Acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics.
Written by a world leader in this field, this book is a vital resource for researchers in medicinal chemistry, chemical biology, structural biology, drug discovery, and pharmacology in cancer and other therapeutic areas, as well as for chemists and biologists working on nucleic acids, and will be useful for both active researchers and students in these areas.
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Book Description Hardcover. Condition: Fine. 0123751381 Fine/As New; Hardcover; Covers are still glossy with "sharp" edge-corners; Unblemished textblock edges; The endpapers and all text pages are bright and unmarked; Binding is tight with a straight spine; This book will be stored and delivered in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); Blue and dark gray covers with title in white lettering; 2011, Academic Press; 208 pages; "Therapeutic Applications of Quadruplex Nucleic Acids," by Stephen Neidle. Seller Inventory # SKU-U31KE08603177
Book Description Hardcover. Condition: As New. No Jacket. 1st Edition. Hardcover. Textbook in As New condition - no jacket, as issued - does NOT contain interior writing/highlighting. This volume gives a uniquely integrated view of quadruplex nucleic acids and will be a major resource in future drug-discovery strategies. Seller Inventory # A015
Book Description hardcover. Condition: Like New. Like New. book. Seller Inventory # D8S0-3-M-0123751381-5