Transgenic Animal Technology: A Laboratory Handbook - Hardcover

Pinkert, Carl A.

Hardcover

ISBN 10: 0124104908 ISBN 13: 9780124104907

Publisher: Elsevier, 2014

Synopsis

Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions. This well-illustrated handbook covers the technical aspects of gene transfer ― from molecular methods to whole animal considerations ― for important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students. This second edition incorporates updates on a variety of genetic engineering technologies ranging from microinjection and ES cell transfer to nuclear transfer in a broad range of animal modeling systems.

• Contains a comprehensive collection of transgenic animal and gene transfer methods
• Discusses background and introduction to techniques and animal systems
• Teaches practical step-by-step protocols
• Fully revised with updates to reflect state-of-the-art technology and associated changes to date

About this title

From the Back Cover:

Transgenic animal technologies and the ability to introduce functional genes into animals have revolutionized our ability to address complex biomedical and biological questions, as well as to make practical applications to production agriculture. This well-illustrated handbook covers the technical aspects of gene transfer in animals-from molecular methods to whole animal considerations-for the important laboratory and domestic animal species. It describes methodologies as employed by leading laboratories and is a key resource for researchers, as well as a tool for training technicians and students.
Key Features
* Contains a comprehensive collection of transgenic animal and gene transfer methods
* Discusses background and introduction to techniques and animal systems
* Teaches practical step-by-step protocols
* Describes mouse model systems
* Covers laboratory and domestic animal species, including:
* Rabbits and rats
* Poultry and fish
* Swine and ruminants
* Illustrated with diagrams and photographs
* Includes useful tables and charts

About the Author:

Dr. Pinkert joined the University of Alabama (UA) in 2013 where he serves as Vice President for Research and Economic Development, and where he is a tenured Professor in the Department of Biological Sciences in the College of Arts and Sciences.

He earned his Ph.D. from the University of Georgia and was a postdoctoral fellow at the University of Pennsylvania. For over 30 years, his research revolved around animal modeling and transgenesis. He has published extensively on transgenic modeling, reproductive biology, and embryology of laboratory and domestic animals. His laboratory developed a number of enabling technologies for the genetic engineering of both nuclear and mitochondrial genomes, as well as mitochondrial modeling strategies to address human developmental and metabolic diseases.

He served as an editor of Transgenic Research on the editorial boards of five others. His research was funded by NIH, USDA, NSF, private foundations and industry. He was a Sigma Xi national lecturer from 1993-1995 and a recipient of the 1997 Doerenkamp-Zbinden Foundation Research Prize (awarded for biomedical research that significantly impacts on the welfare and well-being of animals used in research). He was elected a fellow of the American Association for the Advancement of Science (AAAS) in 2011.

About this edition

• Publisher: Elsevier
• Publication date: 2014
• ISBN 10: 0124104908
• ISBN 13: 9780124104907
• Binding: Hardcover
• Edition number: 3
• Number of pages: 714