During the past decade, physiological methods for performing fine-scale comparative studies of neurons have primarily involved the electrode impalement of one or two randomly positioned neurons in vivo<$> or in brain preparations in vitro.<$> While these approaches have yielded invaluable information, a continuing need exists for technological improvements in this area.
Experimental systems for cultured mammalian neurons that simultaneously provide long-term viability, amenability to biochemical/biophysical manipulation, and precise structural control will be extremely valuable. Recent interdisciplinary work involvingneurobiology, surface chemistry, physics, and electrical engineering has produced unique solutions to problems in neuroscience, and in other areas.
Enabling Technologies for Cultured Neural Networks<$> is the first integrated compilation of recent technological advances relevant to the control and study of mammalian neurons in vitro,<$> providing extensive coverage of the design, fabrication,and use of integrated microelectronic devices in neurobiology. The book explores recent technological advances relevant to the control and study of mammalian neurons in vitro,<$> including:
The isolation and controlled survival, growth, and physiology of cultured mammalian neurons, including geometrically controlled growth of neurons using surface chemistry and micromachiningImproved, non-invasive neuronal stimulation and recording methods, including advanced microelectrode and optical techniquesTheoretical and experimental frameworks for modeling and analyzing the data obtained from these networks
This text will prove important to students and researchers involved in neuron culture, non-neuron culture neuroscientists seeking a new source of information on techniques applicable to preparations other than cultured neurons, to chemists interested inbiological interfaces, and to those in the biomedical engineering field interested in the inherent interdisciplinary nature of the field.
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Book Description Academic Press, 1994. Hardcover. Book Condition: New. book. Bookseller Inventory # 0126659702