This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods providing a a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.
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Lorenzo Galluzzi received his Ph.D. in 2008 from the University of Paris Sud/Paris XI, France, and now works as a Research Manager in the laboratory of Guido Kroemer. He is particularly fascinated by several aspects of mitochondrial cell death, oncometabolism and tumor immunology.
Guido Kroemer received his M.D. in 1985 from the University of Innsbruck, Austria, and his Ph.D. in 1992 from the Autonomous University of Madrid, Spain. He now works as a Research Director at the French Medical Research Council (INSERM) in Villejuif, France, as a Full Professor at the University of Paris Descartes, France, and as a hospital practitioner at the Hôpital Européen George-Pompidou, Paris, France. His research interests encompass mitochondrial cell death, autophagy and the immune response to dying cancer cells.
"Apoptosis, Cancer & Immunity” Laborator, Team 11, Equipe labellisée Ligue contre le Cancer, INSERM Cordeliers Research Cancer Paris, France; Cell Biology & Metabolomics Platform, Gustave Roussy Comprehensive Cancer Center, Villejuif, France; Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France; Université Paris Descartes, Sorbonne Paris Cité, Paris, France
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Book Description Academic Press, 2014. Hardback. Book Condition: NEW. 9780128013298 384pp., Hardback, This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE0895807
Book Description Academic Pr, 2014. Hardcover. Book Condition: Brand New. 1st edition. 358 pages. 9.25x6.25x1.00 inches. In Stock. Bookseller Inventory # zk012801329X
Book Description 2014. Hardcover. Book Condition: New. 1. 15.88 x 23.5 cm. Our orders are sent from our warehouse locally or directly from our international distributors to allow us to offer you the best possible price and delivery time. Book. Bookseller Inventory # MM-21686415
Book Description Academic Press, 2014. Hardcover. Book Condition: New. book. Bookseller Inventory # 012801329X
Book Description Academic Press, 2014. Book Condition: New. Brand New, Unread Copy in Perfect Condition. A+ Customer Service! Summary: This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. Bookseller Inventory # ABE_book_new_012801329X