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Asociacion de Polimorfismos de Ts y Hif-1 Con El Cancer de Pancreas

Jaime Ruiz-Tovar

Published by Ewe Editorial Acad MIA Espa Ola
ISBN 10: 3845484667 / ISBN 13: 9783845484662
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Title: Asociacion de Polimorfismos de Ts y Hif-1 ...

Publisher: Ewe Editorial Acad MIA Espa Ola

Binding: Paperback

Book Condition: New

Book Type: Paperback

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Paperback. 160 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.El cncer de pncreas presenta la peor tasa de supervivencia de todas las neoplasias. Las causas principales de este mal pronstico son el diagnstico tardo, debido a su localizacin anatmica y la falta de especificidad de los sntomas que provoca, y la diseminacin precoz a ganglios linfticos regionales, al hgado y a estructuras vasculares prximas. Se ha postulado que el cncer de pncreas podra estar relacionado con el metabolismo de los folatos y la angiognesis; el gen de la Timidilato Sintasa (TS) controla el metabolismo de los folatos y la sntesis de ADN; el gen del Factor Inducible por Hipoxia (HIF-1 ) regula la respuesta celular a la hipoxia. Los objetivos de este trabajo son analizar las distribuciones genotpicas de los polimorfismos de TS y HIF-1 en pacientes diagnosticados de cncer de pncreas y compararlas con las de un grupo de voluntarios sanos representando a la poblacin general, estudiar la asociacin entre polimorfismos y variables clnico-patolgicas en los pacientes con cncer de pncreas, y determinar la relacin de los polimorfismos con la supervivencia. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783845484662

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