Stock Image

Cartilage and Osteoarthritis

Published by Humana Press Inc.
ISBN 10: 1617374504 / ISBN 13: 9781617374500
New / Paperback / Quantity Available: 20
From BuySomeBooks (Las Vegas, NV, U.S.A.)
Available From More Booksellers
View all  copies of this book
Add to basket
List Price: US$
Price: US$ 274.33
Convert Currency
Shipping: US$ 3.95
Within U.S.A.
Destination, Rates & Speeds

30 Day Returns Policy

Save for Later

About the Book

Bibliographic Details


Title: Cartilage and Osteoarthritis

Publisher: Humana Press Inc.

Binding: Paperback

Book Condition: New

Book Type: Paperback

Description:

Paperback. 358 pages. Dimensions: 8.9in. x 6.1in. x 0.9in.Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9781617374500

About this title:

Book ratings provided by GoodReads:
0 avg rating
(0 ratings)

Synopsis: Osteoarthritis (OA), the most common form of arthritis, is generally characterized by a slowly progressive degeneration of articular cartilage, particularly in the weight-bearing joints. It has a stronger prevalence in women, and its incidence increases with age. OA is a major and growing health concern in developed countries, owing to steadily increasing life expectancy and the demand for better quality of life. Because of its chronic nature and nonfatal outcome, OA affects the growing population of the elderly over an increasing time span. Moreover, despite its relatively benign character, OA is one of the most disabling diseases; it is responsible for increasing financial and social burdens in terms of medical treatments, forced inactivity, loss of mobility, and dependence. Despite a growing awareness of OA as a medical problem that has yet to reach its maximum impact on society, there is a surprising absence of effective medical treatments beyond pain control and surgery. So far, only symptom-modifying drugs are available, while there remains a major demand for disease-modifying treatments of proven clinical efficacy. This demand will hopefully be met in the future by some of the drugs that have been pressed into development and are now at different stages of clinical investigation. Nevertheless, the current lack of effective treatments reflects a still insufficient knowledge of cartilage with respect to its metabolism, interactions with other joint tissues, and causes and mechanisms (possibly of very different nature) leading to failure of its turnover.

Contenuti: Culture and Phenotyping of Chondrocytes in Primary Culture Sylvie Thirion and Francis Berenbaum Culture of Chondrocytes in Alginate Beads Frédéric De Ceuninck, Christophe Lesur, Philippe Pastoureau, Audrey Caliez, and Massimo Sabatini Immortalization of Human Articular Chondrocytes for Generation of Stable, Differentiated Cell Lines Mary B. Goldring Culture of Immortalized Chondrocytes and Their Use As Models of Chondrocyte Function Mary B. Goldring Generation of Pluripotent Stem Cells and Their Differentiation to the Chondrocytic Phenotype Luis A. Solchaga, Jean F. Welter, Donald P. Lennon, and Arnold I. Caplan Semiquantitative Analysis of Gene Expression in Cultured Chondrocytes by RT-PCR Gaëlle Rolland-Valognes Quantification of mRNA Expression Levels in Articular Chondrocytes With PCR Technologies Audrey McAlinden, Jochen Haag, Brigitte Bau, Pia M. Gebhard, and Thomas Aigner RNA Extraction From Cartilage Frédéric Mallein-Gerin and Jérôme Gouttenoire Gene Expression Analysis in Cartilage by In Situ Hybridization Frédéric Mallein-Gerin and Jérôme Gouttenoire Analysis of Differential Gene Expression in Healthy and Osteoarthritic Cartilage and Isolated Chondrocytes by Microarray Analysis Thomas Aigner, Joachim Saas, Alexander Zien, Ralf Zimmer, Pia M. Gebhard, and Thomas Knorr High-Efficiency Nonviral Transfection of Primary Chondrocytes Jean F. Welter, Luis A. Solchaga, and Matthew C. Stewart In Vitro Gene Transfer to Chondrocytes and Synovial Fibroblasts by Adenoviral Vectors Jean-Noel Gouze, Martin J. Stoddart, Elvire Gouze, Glyn D. Palmer, Steven C. Ghivizzani, Alan J. Grodzinsky, and Christopher H. Evans Changes of Chondrocyte Metabolism In Vitro: An Approach by Proteomic Analysis Anne-Marie Freyria and Michel Becchi Analysis of ChondrocyteFunctional Markers and Pericellular Matrix Components by Flow Cytometry Gust Verbruggen, Jun Wang, Lai Wang, Dirk Elewaut, and Eric M. Veys A Simple and Reliable Assay of Proteoglycan Synthesis by Cultured Chondrocytes Frédéric De Ceuninck and Audrey Caliez Assays of Proteoglycan and Collagen Degradation in Cultures of Rabbit Cartilage Explants Christophe Lesur and Massimo Sabatini Production of Antibodies Against Degradative Neoepitopes in Aggrecan John S. Mort and Peter J. Roughley Immunoassays for Collagens in Chondrocyte and Cartilage Explant Cultures R. Clark Billinghurst, Fackson Mwale, Anthony Hollander, Mirela Ionescu, and A. Robin Poole Detection of Apoptosis in Cartilage In Situ and in Isolated Chondrocytes Darryl D. D'Lima, Klaus Kuhn, and Martin K. Lotz Expression, Activity, and Regulation of MAP Kinases in Cultured Chondrocytes Jang-Soo Chun Mechanical Loading of Chondrocytes Embedded in 3D Constructs: In Vitro Methods for Assessment of Morphological and Metabolic Response to Compressive Strain David A. Lee and Martin M. Knight In Vitro Physical Stimulation of Tissue-Engineered and Native Cartilage Kelvin W. Li, Travis J. Klein, Kanika Chawla, Gayle E. Nugent, Won C. Bae, and Robert L. Sah Index

"About this title" may belong to another edition of this title.

Bookseller & Payment Information

Payment Methods

This bookseller accepts the following methods of payment:

  • American Express
  • MasterCard
  • Visa

[Search this Seller's Books]

[List this Seller's Books]

[Ask Bookseller a Question]

Bookseller: BuySomeBooks
Address: Las Vegas, NV, U.S.A.

AbeBooks Bookseller Since: May 21, 2012
Bookseller Rating: 5-star rating

Terms of Sale:

We guarantee the condition of every book as it's described on the Abebooks web
sites. If you're dissatisfied with your purchase (Incorrect Book/Not as
Described/Damaged) or if the order hasn't arrived, you're eligible for a refund
within 30 days of the estimated delivery date. If you've changed your mind about a book that you've ordered, please use the Ask bookseller a question link to contact us and we'll respond within 2 business days.

BuySomeBooks is operated by Drive-On-In, Inc., a Nevada co...

[More Information]

Shipping Terms:

Orders usually ship within 1-2 business days. Books are shipped from multiple locations so your order may arrive from Las Vegas,NV, Roseburg,OR, La Vergne,TN, Momence,IL, or Commerce,GA.


Store Description: BuySomeBooks is great place to get your books online. With over eight million titles available we're sure to have what you're looking for. Despite having a large selection of new books available for immediate shipment and excellent customer service, people still tell us they prefer us because of our prices.