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Gene Expression Analysis in Diffuse Large B-Cell Lymphoma

Helena Hauge

Published by LAP LAMBERT Academic Publishing
ISBN 10: 3843374767 / ISBN 13: 9783843374767
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Title: Gene Expression Analysis in Diffuse Large ...

Publisher: LAP LAMBERT Academic Publishing

Binding: Paperback

Book Condition: New

Book Type: Paperback

Description:

Paperback. 72 pages. Dimensions: 8.7in. x 5.9in. x 0.2in.Follicular lymphoma (FL) represents the most common low-grade Non-Hodgkins lymphoma. FLs are of B cell origin, generally incurable, and frequently transform to high-grade diffuse large B cell lymphoma (DLBCL). Transformation is generally correlated with poor prognosis and the molecular mechanisms involved are largely unknown. This book gives an introduction to the field of carcinogenesis with focus on the events leading to Non-Hodgkins lymphoma and presents the results of a study aimed at identifying novel genes differentially expressed in patient-matched biopsies of FL and DLBCL to increase the understanding of disease progression. A general discussion of the methods applied, including the subtraction methodology cDNA Representational Difference Analysis (cDNA RDA), and the findings from this study are included. This book should be of interest to anyone who wants to get an understanding of the processes causing normal cells to transform into cancer cells and how studies of gene expression can highlight these issues. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783843374767

About this title:

Synopsis: Follicular lymphoma (FL) represents the most common low-grade Non-Hodgkin's lymphoma. FLs are of B cell origin, generally incurable, and frequently transform to high-grade diffuse large B cell lymphoma (DLBCL). Transformation is generally correlated with poor prognosis and the molecular mechanisms involved are largely unknown. This book gives an introduction to the field of carcinogenesis with focus on the events leading to Non-Hodgkin's lymphoma and presents the results of a study aimed at identifying novel genes differentially expressed in patient-matched biopsies of FL and DLBCL to increase the understanding of disease progression. A general discussion of the methods applied, including the subtraction methodology cDNA Representational Difference Analysis (cDNA RDA), and the findings from this study are included. This book should be of interest to anyone who wants to get an understanding of the processes causing normal cells to transform into cancer cells and how studies of gene expression can highlight these issues.

About the Author: Helena Hauge, phd: Studied cell biology at the University of Oslo, Norway. She is at present post doc at the Section for virology and serology, The National Veterinary Institute, Oslo, Norway

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