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Safety of Synthetic Food Colorant Tartrazine Is in Question

Surya Parakkot Ramakrishnan

Published by LAP Lambert Academic Publishing
ISBN 10: 3659218723 / ISBN 13: 9783659218729
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Title: Safety of Synthetic Food Colorant Tartrazine...

Publisher: LAP Lambert Academic Publishing

Binding: Paperback

Book Condition: New

Book Type: Paperback

Description:

Paperback. 72 pages. Dimensions: 8.7in. x 5.9in. x 0.2in.An efficient and accurate Reverse Phase High Performance Liquid Chromatographic method was developed and validated for the separation and determination of synthetic food colorant Tartrazine(E102)in certain food stuff and in drugs. This method was successfully applied for the estimation of tartrazine dye in certain food stuff (cream biscuits, Tang, gems, and candies) and in drugs (Aceclofenac and Metoprolol tablets - in which tartrazine was present as a coating agent). Interaction study was carried out to find the effect of tartrazine on the protein binding of Drugs in Bovine serum albumin. The objective of this research was to estimate the tartrazine dye in various food stuff and formulation, and to determine the effect of dye on drug. Tartrazine extracted and quantified in various food stuff. The amount of E102 present in Aceclofenac and metoprolol tablet was also estimated. A study on protein binding of drugs by UV spectroscopy and RP-HPLC were conducted. The effect of tartrazine on protein binding of Aceclofenac and Metoprolol in BSA and were carried out and determined that Protein binding of the drugs was altered by the effect of dye. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783659218729

About this title:

Synopsis: An efficient and accurate Reverse Phase - High Performance Liquid Chromatographic method was developed and validated for the separation and determination of synthetic food colorant Tartrazine(E102)in certain food stuff and in drugs. This method was successfully applied for the estimation of tartrazine dye in certain food stuff (cream biscuits, Tang, gems, and candies) and in drugs (Aceclofenac and Metoprolol tablets - in which tartrazine was present as a coating agent). Interaction study was carried out to find the effect of tartrazine on the protein binding of Drugs in Bovine serum albumin. The objective of this research was to estimate the tartrazine dye in various food stuff and formulation, and to determine the effect of dye on drug.Tartrazine extracted and quantified in various food stuff. The amount of E102 present in Aceclofenac and metoprolol tablet was also estimated. A study on protein binding of drugs by UV spectroscopy and RP-HPLC were conducted.The effect of tartrazine on protein binding of Aceclofenac and Metoprolol in BSA and were carried out and determined that Protein binding of the drugs was altered by the effect of dye.

About the Author: Dr.Surya Parakkot Ramakrishnan is pursuing Ph.D in pharmacy in(2012-2015).She is the author of several articles published in international and national journals and is a member of APTI.She was born in May/05/1979 at Ottapalam,in Kerala,India.She is the youngest child of her Parents Mrs P.K.Thankam (School teacher)& Mr P.N.Ramakrishnan(Post Master).

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