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Spect de Neurotransmision: Utilidad En La Evaluacion de Psicofamarcos

Mar√a Penengo

Published by Ewe Editorial Acad MIA Espa Ola
ISBN 10: 3847358332 / ISBN 13: 9783847358336
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Title: Spect de Neurotransmision: Utilidad En La ...

Publisher: Ewe Editorial Acad MIA Espa Ola

Binding: Paperback

Book Condition: New

Book Type: Paperback

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Paperback. 52 pages. Dimensions: 8.7in. x 5.9in. x 0.1in.Este trabajo forma parte de la tesina presentada por la autora en Agosto 2003 en el curso del Programa de Doctorado en Farmacologa de la Universidad Autnoma de Barcelona. Mantiene su vigencia hoy ya que la utilizacin de tcnicas de neuroimagen en el desarrollo de psicofrmacos permite delinear perfiles de unin a receptores y determinar los regmenes de dosificacin e intervalos de dosis eficaces ms probables. En este trabajo se determinan las caractersticas de captacin del ligando 123I-IBZM (iodo-123(S)-(-)-2-hidroxi-3-iodo-6-metoxi-N(1-etil-2-pirrolidinil)metil-benzamida) utilizando Tomografa Computarizada de Emisin de Fotn nico (SPECT) en un grupo de voluntarios sanos (n10) y se verifica la idoneidad en la eleccin del intervalo de tiempo de 90 a 120 minutos post-inyeccin de 123I-IBZM para realizar la estimacin de la densidad de receptores dopaminrgicos D2D3 cerebrales. Adems, se obtienen valores preliminares de ocupacin de receptores D2 (OR D2) en pacientes esquizofrnicos (n8) tratados con clozapina (50-350 mgda) y olanzapina (5-15 mgda) a diferentes tiempos tras la ltima dosis de medicacin. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN. Bookseller Inventory # 9783847358336

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