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Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2010
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: Lucky's Textbooks, Dallas, TX, U.S.A.
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Published by Südwestdeutscher Verlag für Hochschulschriften, 2010
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: Ria Christie Collections, Uxbridge, United Kingdom
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Condition: New. PRINT ON DEMAND Book; New; Fast Shipping from the UK. No. book.
Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2009
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: PBShop.store US, Wood Dale, IL, U.S.A.
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PAP. Condition: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Sudwestdeutscher Verlag fur Hochschulschrifte 2009-10, 2009
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: Chiron Media, Wallingford, United Kingdom
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PF. Condition: New.
Published by Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG Okt 2015, 2015
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Germany
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Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and regulation of confluence-dependent nuclear location of RS1 was investigated. Nuclear location of RS1 was found to be regulated by the cell cycle. A nuclear shuttling signal (NS) in pRS1 was identified that mediates translocation of RS1 into and out of the nucleus via importin ß1 and CRM1, respectively. The adjacent protein kinase C (PKC) phosphorylation site was shown to control nuclear localization driven by NS during confluence. According to the proposed model, in subconfluent cells, RS1 is actively imported into the nucleus whereas nuclear export of RS1 is not active. After confluence, phosphorylation of serine 370 of pRS1 by PKC takes place leading to enhancement of RS1 nuclear export and predominantly cytoplasmic distribution of the protein. Gene expression profiling of mouse embryonic fibroblasts with RS1-/- genotype suggests that transcriptional regulation by RS1 might be important for the cell cycle and cell division. Thus, RS1 might play a role in the regulation of the solute carriers during specific phases of the cell cycle. 112 pp. Deutsch.
Published by Südwestdeutscher Verlag Für Hochschulschriften AG Co. KG, 2010
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: AHA-BUCH GmbH, Einbeck, Germany
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Taschenbuch. Condition: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and regulation of confluence-dependent nuclear location of RS1 was investigated. Nuclear location of RS1 was found to be regulated by the cell cycle. A nuclear shuttling signal (NS) in pRS1 was identified that mediates translocation of RS1 into and out of the nucleus via importin ß1 and CRM1, respectively. The adjacent protein kinase C (PKC) phosphorylation site was shown to control nuclear localization driven by NS during confluence. According to the proposed model, in subconfluent cells, RS1 is actively imported into the nucleus whereas nuclear export of RS1 is not active. After confluence, phosphorylation of serine 370 of pRS1 by PKC takes place leading to enhancement of RS1 nuclear export and predominantly cytoplasmic distribution of the protein. Gene expression profiling of mouse embryonic fibroblasts with RS1-/- genotype suggests that transcriptional regulation by RS1 might be important for the cell cycle and cell division. Thus, RS1 might play a role in the regulation of the solute carriers during specific phases of the cell cycle.
Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2009
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: PBShop.store UK, Fairford, GLOS, United Kingdom
Book Print on Demand
PAP. Condition: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.
Published by Südwestdeutscher Verlag für Hochschulschriften, 2015
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: moluna, Greven, Germany
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Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The RS1 protein participates in regulation of Na+-D-glucose cotransporter SGLT1 and other solute carriers. In the present study, the mechanism and regulation of confluence-dependent nuclear location of RS1 was investigated. Nuclear location of RS1 was found.
Published by Suedwestdeutscher Verlag fuer Hochschulschriften, 2010
ISBN 10: 3838111613ISBN 13: 9783838111612
Seller: Mispah books, Redhill, SURRE, United Kingdom
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Paperback. Condition: Like New. Like New. book.