springer new york sep 2016 (377 results)

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents fundamental concepts and seminal results to the study of vortex filaments in equilibrium. It also presents new discoveries in quasi-2D vortex structures with applications to geophysical fluid dynamics and magnetohydrodynamics in plasmas. It fills a gap in the vortex statistics literature by simplifying the mathematical introduction to this complex topic, covering numerical methods, and exploring a wide range of applications with numerous examples. The authors have produced an introduction that is clear and easy to read, leading the reader step-by-step into this topical area. Alongside the theoretical concepts and mathematical formulations, interesting applications are discussed. This combination makes the text useful for students and researchers in mathematics and physics. 152 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This handbook consists of seventeen chapters written by eminent scientists from the international mathematical community, who present important research works in the field of mathematical analysis and related subjects, particularly in the Ulam stability theory of functional equations. The book provides an insight into a large domain of research with emphasis to the discussion of several theories, methods and problems in approximation theory, analytic inequalities, functional analysis, computational algebra and applications.The notion of stability of functional equations has its origins with S. M. Ulam, who posed the fundamental problem for approximate homomorphisms in 1940 and with D. H. Hyers, Th. M. Rassias, who provided the first significant solutions for additive and linear mappings in 1941 and 1978, respectively. During the last decade the notion of stability of functional equations has evolved into a very active domain of mathematical research with several applications of interdisciplinary nature.The chapters of this handbook focus mainly on both old and recent developments on the equation of homomorphism for square symmetric groupoids, the linear and polynomial functional equations in a single variable, the Drygas functional equation on amenable semigroups, monomial functional equation, the Cauchy-Jensen type mappings, differential equations and differential operators, operational equations and inclusions, generalized module left higher derivations, selections of set-valued mappings, D'Alembert's functional equation, characterizations of information measures, functional equations in restricted domains, as well as generalized functional stability and fixed point theory. 408 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The implicit function theorem is one of the most important theorems in analysis and its many variants are basic tools in partial differential equations and numerical analysis.This second edition of Implicit Functions and Solution Mappings presents an updated and more complete picture of the field by including solutions of problems that have been solved since the first edition was published, and places old and new results in a broader perspective. The purpose of this self-contained work is to provide a reference on the topic and to provide a unified collection of a number of results which are currently scattered throughout the literature. Updates to this edition include new sections in almost all chapters, new exercises and examples, updated commentaries to chapters and an enlarged index and references section. 496 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The second edition of this classic textbook presents a rigorous and self-contained introduction to real analysis with the goal of providing a solid foundation for future coursework and research in applied mathematics. Written in a clear and concise style, it covers all of the necessary subjects as well as those often absent from standard introductory texts. Each chapter features a 'Problems and Complements' section that includes additional material that briefly expands on certain topics within the chapter and numerous exercises for practicing the key concepts.The first eight chapters explore all of the basic topics for training in real analysis, beginning with a review of countable sets before moving on to detailed discussions of measure theory, Lebesgue integration, Banach spaces, functional analysis, and weakly differentiable functions. More topical applications are discussed in the remaining chapters, such as maximal functions, functions of bounded mean oscillation, rearrangements, potential theory, and the theory of Sobolev functions. This second edition has been completely revised and updated and contains a variety of new content and expanded coverage of key topics, such as new exercises on the calculus of distributions, a proof of the Riesz convolution, Steiner symmetrization, and embedding theorems for functions in Sobolev spaces. Ideal for either classroom use or self-study, Real Analysis is an excellent textbook both for students discovering real analysis for the first time and for mathematicians and researchers looking for a useful resource for reference or review.Praise for the First Edition:'[This book] will be extremely useful as a text. There is certainly enough material for a year-long graduate course, but judicious selection would make it possible to use this most appealing book in a one-semester course for well-prepared students.'-Mathematical Reviews 628 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Pell and Pell-Lucas numbers, like the well-known Fibonacci and Catalan numbers, continue to intrigue the mathematical world with their beauty and applicability. They offeropportunities for experimentation, exploration, conjecture, and problem-solving techniques, connecting the fields of analysis, geometry, trigonometry, andvarious areas of discrete mathematics,number theory, graph theory, linear algebra, and combinatorics. Pell and Pell-Lucas numbers belong to an extended Fibonacci family as a powerful tool for extracting numerous interesting properties of a vast array of number sequences.Akey feature of this work is the historical flavor that is interwoven into the extensive and in-depth coverage of the subject.An interesting array of applications to combinatorics, graph theory, geometry, and intriguing mathematical puzzles is another highlight engaging the reader. The exposition is user-friendly, yet rigorous, so that a broad audience consisting of students, math teachers and instructors, computer scientists and other professionals, along with the mathematically curious will all benefit from this book.Finally, Pell and Pell-Lucas Numbers provides enjoyment and excitement while sharpening the reader's mathematical skills involving pattern recognition, proof-and-problem-solving techniques. 456 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book gives an introduction to the very active field of combinatorics of affine Schubert calculus, explains the current state of the art, and states the current open problems. Affine Schubert calculus lies at the crossroads of combinatorics, geometry, and representation theory. Its modern development is motivated by two seemingly unrelated directions. One is the introduction of k-Schur functions in the study of Macdonald polynomial positivity, a mostly combinatorial branch of symmetric function theory. The other direction is the study of the Schubert bases of the (co)homology of the affine Grassmannian, an algebro-topological formulation of a problem in enumerative geometry.This is the first introductory text on this subject. It contains many examples in Sage, a free open source general purpose mathematical software system, to entice the reader to investigate the open problems. This book is written for advanced undergraduate and graduate students, as well as researchers, who want to become familiar with this fascinating new field. 228 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Rooted in a pedagogically successful problem-solving approach to linear algebra, the present work fills a gap in the literature that is sharply divided between elementary texts and books that are too advanced to appeal to a wide audience. It clearly develops the theoretical foundations of vector spaces, linear equations, matrix algebra, eigenvectors, and orthogonality, while simultaneously emphasizing applications and connections to fields such as biology, economics, computer graphics, electrical engineering, cryptography, and political science.Ideal as an introduction to linear algebra, the extensive exercises and well-chosen applications also make this text suitable for advanced courses at the junior or senior undergraduate level. Furthermore, it can serve as a colorful supplementary problem book, reference, or self-study manual for professional scientists and mathematicians. Complete with bibliography and index, 'Essential Linear Algebra with Applications' is a natural bridge between pure and applied mathematics and the natural and social sciences, appropriate for any student or researcher who needs a strong footing in the theory, problem-solving, and model-building that are the subject's hallmark. 504 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Remediation in medical education is the act of facilitating a correction for trainees who started out on the journey toward becoming excellent physicians but have moved off course. This book offers an evidence-based and practical approach to the identification and remediation of medical trainees who are unable to perform to standards. As assessment of clinical competence and professionalism has become more sophisticated and ubiquitous, medical educators increasingly face the challenge of implementing effective and respectful means to work with trainees who do not yet meet expectations of the profession and society.Remediation in Medical Education: A Mid-Course Correction describes practical stepwise approaches to remediate struggling learners in fundamental medical competencies; discusses methods used to define competencies and the science underlying the fundamental shift in the delivery and assessment of medical education; explores themes that provide context for remediation, including professional identity formation and moral reasoning, verbal and nonverbal learning disabilities, attention deficit disorders in high-functioning individuals, diversity, and educational and psychiatric topics; and reviews system issues involved in remediation, including policy and leadership challenges and faculty development. 404 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This comprehensive reference delves into the complex process of medical decision making-both the nuts-and-bolts access and insurance issues that guide choices and the cognitive and affective factors that can make patients decide against their best interests. Wide-ranging coverage offers a robust evidence base for understanding decision making across the lifespan, among family members, in the context of evolving healthcare systems, and in the face of life-changing diagnosis. The section on applied decision making reviews the effectiveness of decision-making tools in healthcare, featuring real-world examples and guidelines for tailored communications with patients. Throughout, contributors spotlight the practical importance of the field and the pressing need to strengthen health decision-making skills on both sides of the clinician/client dyad.Among the Handbook's topics: From laboratory to clinic and back: connecting neuroeconomic and clinical measures of decision-making dysfunctions. Strategies to promote the maintenance of behavior change: moving from theoretical principles to practices. Shared decision making and the patient-provider relationship. Overcoming the many pitfalls of communicating risk. Evidence-based medicine and decision-making policy. The internet, social media, and health decision making. The Handbook of Health Decision Science will interest a wide span of professionals, among them health and clinical psychologists, behavioral researchers, health policymakers, and sociologists. 392 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware - This book discusses current research on identity formation, family and peer influences, risk and resilience factors, and concepts of masculinity and sexuality in African American boys. Sorting out genuine findings from popular misconceptions and misleading headlines, this concise and wide-ranging reference covers the crucial adolescent years, ages 11-16, acknowledging diversity of background and experience in the group, and differences and similarities with African American girls as well as with other boys. In addition, the authors review strengths-based school and community programs that harness evidence and insights to promote pro-social behavior. Featured areas of coverage include: The protective role of ethnic identity and racial socialization.Family management, cohesion, communication, and well-being.Development and importance of peer relationships.Health and well-being.Theoretical perspectives on educational achievement.Factors that contribute to delinquency and victimization.What works: effective programs and practices.African American Boys is an essential resource for a wide range of clinicians and practitioners - as well as researchers and graduate students - in school and clinical child psychology, prevention and public health, social work, mental health therapy and counseling, family therapy, and criminal justice. 188 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This manual provides laboratory-based learning experiences in perceptually and psychosocially linked exercise assessment, prescription, and programming. The primary pedagogic outcome is the ability to use applied theory and practice in perceptual and psychosocial exercise assessment and program design to promote the adoption and maintenance of a physically active lifestyle, enhancing overall health fitness. Perceptual and psychosocial variables are presented in individual, stand-alone laboratory modules that can supplement existing curricula such as exercise and sport psychology, exercise physiology, exercise testing and prescription, and exercise training and conditioning. In addition, the complete modular set has a conceptual flow that allows its presentation as an entire, laboratory-based course. The laboratory modules are divided into three primary units: assessment (theoretical constructs, scales and procedures, tests), prescription (self-regulation, performance), and program evaluation. The manual uses a unique format in which case studies are embedded in the conceptual flow of each lab module facilitating translation of laboratory results to real-world application. The manual concludes with a discussion of perceptually and psychosocially linked exercise prescription and programming applications in public health, such as program monitoring and adherence. 344 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book the authors introduce and explain many methods and models for the development of Information Systems (IS). It was written in large part to aid designers in designing successful devices/systems to match user needs in the field. Chief among these are website development, usability evaluation, quality evaluation and success assessment. The book provides great detail in order to assist readers' comprehension and understanding of both novel and refined methodologies by presenting, describing, explaining and illustrating their basics and working mechanics. Furthermore, this book presents many traditional methods and methodologies in an effort to make up a comprehensive volume on High Level Models and Methodologies for Information Systems.The target audience for this book is anyone interested in conducting research in IS planning and development. The book represents a main source of theory and practice of IS methods and methodologies applied to these realities. The book will appeal to a range of professions that are involved in planning and building the information systems, for example information technologists, information systems developers, as well as Web designers and developers-both researchers and practitioners; as a consequence, this book represents a genuinely multi-disciplinary approach to the field of IS methods and methodologies. 164 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The movements toward cultural sensitivity and evidence-based practice are watershed developments in clinical psychology. As a population with a long history of substandard treatment from mental health systems, African Americans have especially benefitted from these improvements. But as with other racial and ethnic minorities, finding relevant test measures in most psychological domains presents clinicians with an ongoing challenge. The Guide to Psychological Assessment with African Americans aims to close the evaluation/therapy gap by giving practitioners the tools to choose appropriate instruments while respecting client individuality. Expert contributors analyze scarce and far-flung data, identify strengths and limitations of measures and norms in their use with African-American clients, and advise on avoiding biases in interpreting results. The editors advocate for a theory-based hypothesis-testing approach to assessment when empirical evidence is lacking, and offer guidelines for decision-making that is effective as well as ethnically aware. The Guide's findings, insights, and practical information cover the gamut of test and diagnostic areas, including: IQ and personality.Generalized anxiety disorder, panic, and phobias.Neuropsychological assessment, cognitive decline, and dementia.Mood disorders and suicidality.Forensic assessment, risk, and recidivism.Measures specific to children and adolescents.Plus PTSD, substance disorders, eating pathology, and more. Expertly complementing cross-cultural treatment texts, the Guide to Psychological Assessment with African Americans stands out as a trustworthy resource for treatment planning useful to clinical psychologists, neuropsychologists, and clinical social workers. 344 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book demonstrates how social distress or anxiety is reflected, modified, and evolves through the medium of the motion picture. Tracing cinema from its earliest forms, the authors show how film is a perfect medium for generating and projecting dreams, fantasies, and nightmares, on the individual as well as the societal level. Arising at the same time as Freud's influential ideas, cinema has been intertwined with the wishes and fears of the greater culture and has served as a means of experiencing those feelings in a communal and taming environment. From Munsterberg's original pronouncements in the early 20th century about the psychology of cinema, through the pioneering films of Melies, the works of the German expressionists, to James Bond and today's superheroes this book weaves a narrative highlighting the importance of the social dream. It develops the idea that no art form goes beyond the ordinary process of consciousness in the same way as film, reflecting, as it does, the cognitive, emotional, and volitional aspects of human nature. 192 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Nature of Language addresses one of the most fundamental questions of mankind: how did language evolve, and what are the neurobiological and cognitive foundations of language processing These questions are explored from different perspectives to discuss the building blocks of language evolution and how they developed in the way they can be found in modern humans. Primarily, neural mapping methods of cognition presented in this research provide extremely valuable data about the neural circuitries that are involved in language processing. Thus, the book explores and illustrates cortical mapping in typical language patterns, but also cortical mapping in atypical populations that fail to process particular language aspects. A neurobiological stance is used to inquire about how language abilities of our species evolved to communicate for the purposes of conveying information such as ideas, emotions, goals, and humor. The evolutionary language model presented builds on the cognitive abilities of our ancestors, and it allows readers to draw a variety of expansive conclusions from that, including the idea that human language as an interface system provides the basis for consciousness. 220 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Evidence pertaining to continual violence throughout the life cycle coupled with the experience of growing old in a life permeated by intimate violence is scarce. And the focus is usually on the victims usually, the older, battered women and seldom on their aging partners or adult children who were part and parcel of the violent dynamics in the family system. With the increase in longevity and the older population's subsequent growth in size, the number of elderly couples living and aging in long-lasting conflictive relationships is on the rise.The relatively intense preoccupation with elder abuse in the gerontological literature in recent years has not specifically addressed long-term intimate violence among the old adults and its lasting consequences. Similarly, the literature on intimate intergenerational relationships in old age has usually focused on normative exchanges between partners and their extended family, including their adult children. Therefore, conflictive relationships, and particularly violent ones, have also fallen outside the scope of this body of research. This volume describes and analyzes the various perspectives of family members concerning life, and particularly old age, in the shadow of long-term intimate violence. It explores how people make sense out of living and aging in violence, how interpersonal, familial and cross-generational relationships are perceived and reconstructed and how 'we-ness' is achieved, if at all, in such families. 152 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -An essential text for researchers and academics seeking the most comprehensive and up-to-date coverage of all aspects of e-learning and ICT in education, this book is a multidisciplinary forum covering technical, pedagogical, organizational, instructional and policy aspects of the topic. Representing the best peer-reviewed papers from the 8th Panhellenic Conference on ICT in Education, special emphasis is given to applied research relevant to educational practice and guided by the educational realities in schools, colleges, universities and informal learning organizations.The volume encompasses the current trends and issues which determine and inform the integration of ICT in educational practice, including educational software, educational games, collaborative learning, virtual learning environments, social networks, learning analytics, digital museums, as well as the evolution of e-learning. 336 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware - The educators are dedicated and concerned. The curriculum is successful. Yet some students aren't reading at grade level, and meetings air problems without making progress. Many students continue to flounder, leading to more meetings with the same lack of meaningful results. The Practitioner's Guide to Curriculum-Based Evaluation in Reading gives researchers and professionals the means to break this frustrating cycle, crafted by authors who have not only been there and done that, but can explain in depth how to replicate the method. Focusing on reading but applicable across subject areas, this highly accessible guide defines curriculum-based evaluation (CBE), provides conceptual background, and analyzes its component steps. Assessment and intervention are given equal attention within a problem-solving model featuring tools for skill assessment, progress monitoring, goal setting, and other bedrock tasks. Chapters build to lead readers beyond classroom strategies to guidelines for problem solving and decision making to effectively address individual student needs. Included in the coverage: The curriculum-based evaluation process.Relating CBE to the Multi-Tier System of Support model.Using CBE in daily practice, both in classwork and schoolwide.Decoding, early literacy, and reading comprehension.Progress monitoring and decision making.Plus FAQs, handouts, and other supplemental materials. This level of educational insight and pedagogical detail make the Practitioner's Guide to Curriculum-Based Evaluation in Reading a clarion call for researchers, graduate students, and professionals in school and clinical child psychology; assessment, testing, and evaluation; applied linguistics; language education; special education and allied education; educational psychology; and social work. 324 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text integrates different mobility data handling processes, from database management to multi-dimensional analysis and mining, into a unified presentation driven by the spectrum of requirements raised by real-world applications. It presents a step-by-step methodology to understand and exploit mobility data: collecting and cleansing data, storage in Moving Object Database (MOD) engines, indexing, processing, analyzing and mining mobility data. Emerging issues, such as semantic and privacy-aware querying and mining as well as distributed data processing, are also covered. Theoretical presentation is smoothly interchanged with hands-on exercises and case studies involving an actual MOD engine. The authors are established experts who address both theoretical and practical dimensions of the field but also present valuable prototype software. The background context, clear explanations and sample exercises make this an ideal textbook for graduate students studying database management, data mining and geographic information systems. 316 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Digital Da Vinci book series opens with the interviews of music mogul Quincy Jones, MP3 inventor Karlheinz Brandenburg, Tommy Boy founder Tom Silverman and entertainment attorney Jay L. Cooper. A strong supporter of science, technology, engineering and mathematics programs in schools, The Black Eyed Peas founding member will.i.am announced in July 2013 his plan to study computer science. Leonardo da Vinci, the epitome of a Renaissance man, was an Italian polymath at the turn of the 16th century. Since the Industrial Revolution in the 18th century, the division of labor has brought forth specialization in the workforce and university curriculums. The endangered species of polymaths is facing extinction. Computer science has come to the rescue by enabling practitioners to accomplish more than ever in the field of music. In this book, Newton Lee recounts his journey in executive producing a Billboard-charting song like managing agile software development; M. Nyssim Lefford expounds producing and its effect on vocal recordings; Dennis Reidsma, Mustafa Radha and Anton Nijholt survey the field of mediated musical interaction and musical expression; Isaac Schankler, Elaine Chew and Alexandre François describe improvising with digital auto-scaffolding; Shlomo Dubnov and Greg Surges explain the use of musical algorithms in machine listening and composition; Juan Pablo Bello discusses machine listening of music; Stephen and Tim Barrass make smart things growl, purr and sing; Raffaella Folgieri, Mattia Bergomi and Simone Castellani examine EEG-based brain-computer interface for emotional involvement in games through music and last but not least, Kai Ton Chau concludes the book with computer and music pedagogy. Digital Da Vinci: Computers in Music is dedicated to polymathic education and interdisciplinary studies in the digital age empowered by computer science. Educators and researchers ought to encourage the new generation of scholars to become as well rounded as a Renaissance man or woman. 288 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This unique title is designed to illustrate and foster how a closer working relationship between pediatricians and subspecialists can make childhood medicine work more seamlessly. Despite the common lack of training for pediatricians in pediatric neurosurgery, they are challenged almost daily with caring for children with neurologic conditions. Common Neurological Conditions in the Pediatric Practice is replete with a wide range of instructional case vignettes and is organized into sections that loosely approximate the neurologic development of a child and address issues that are commonly encountered. The first section reviews neurologic development and birth related trauma commonly seen in the neonatal intensive care unit. The second part addresses findings commonly encountered by a pediatrician in a child's first month of life. The third section is a comprehensive review of hydrocephalus. Part four describes state of the art imaging techniques for the central nervous system in children, from pre-natal ultrasound through MRI and CT; and the fifth part consists of individual explorations of common neurosurgical conditions that many pediatricians are uncomfortable managing, including brain tumors, spasticity, and vascular lesions to use as a reference tool when caring for a complex neurosurgical patient. Finally a series of chapters related to head trauma, including sections on non-accidental trauma and concussion management, completes the text. 460 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents relevantbackground information to understanding the molecular basis governingunconventional protein secretion (UPS), and in particular explores the latesttechniques and protocols that have been successfully applied for the study ofthis topic. Detailed chapters include an overview of conventional andunconventional secretory pathways along with multidisciplinary approaches andmethods used for UPS analysis in different organisms. Written in the highly successful Methods inMolecular Biology series format, chapters include introductions to theirrespective topics, lists of the necessary materials and reagents, step-by-step,readily reproducible laboratory protocols, and tips on troubleshooting andavoiding known pitfalls.Authoritative and cutting-edge, UnconventionalProtein Secretion: Methods and Protocols will be usefulfor all interested in the secretory pathway field as well as applications incell biology, cell development, biomedical research, and healthcare. 288 pp. Englisch.

Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This unique book focuses on the non-myeloma plasma cell dyscrasias. A key resource for this group of diseases, the book features the latest in emerging knowledge and therapeutic developments, including novel therapies. Each disease-specific chapter discusses biology, disease course, and appropriate therapeutic interventions, covering plasma cell leukemia, plasmacytoma, POEMS Syndrome and Castleman's Disease, Waldenström macroglobulinemia, immunoglobin deposition disease, and cryoglobulinemic syndromes, among others. The only book dedicated to this intriguing family of diseases,Biology and Management of Unusual Plasma Cell Dyscrasiaswill be a long-lasting reference for clinicians and scientists alike. 216 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume provides complete coverage of the computational approaches currently used in Synthetic Biology. Chapters focus on computational methods and algorithms for the design of bio-components, insight on CAD programs, analysis techniques, and distributed systems. Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory. Authoritative and practical, Computational Methods in Synthetic Biology serves as a guide to plan in silico the in vivo or in vitro construction of a variety of synthetic bio-circuits. 372 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Receptor Tyrosine Kinases: Methods and Protocols explores on the most widely studied of the protein classes, known for their central role in several cellular functions and in a variety of human pathologies. Beginning with a section on activation and signaling of Receptor Tyrosine Kinases (RTKs), the book continues with chapters on aberrant expression of RTKs, trafficking and negative regulation, as well as RTKs as pharmacological targets. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Receptor Tyrosine Kinases: Methods and Protocols contains an up-to-date overview of the most relevant and widely used methods employed in this field, providing detailed protocols that molecular and cellular biologists could easily adopt in their research programs on RTKs. 196 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Most biological reactions and functions occur within a narrow range of pH. Any changes in the pH have great impacts on the biological functional at every level, including protein folding, enzymatic activities and proliferation and cell death. Therefore, maintain the pH homeostasis at the local or systemic level is one of the highest priorities for all multicellular organisms. Many redundant mechanisms are in place to maintain the pH homeostasis, a topic that is well covered in the scientific literature and medical textbooks. However, when the pH homeostasis is disrupted in various physiological adaptations and pathological situations, resulting acidity may trigger significant pathophysiological events and modulate disease outcomes. Therefore, understanding how various cells sense and react to acidity have broad impact in a wide variety of human diseases, including cancer, stroke, myocardial infarction and diabetes, renal and infectious diseases. In this book, many investigators have summarized the molecular genetics on the detailed mechanisms by which different mammalian cells sense and response acidity. These chapters cover the acidity with broad impact in biological understanding and human diseases and review various sensing mechanism and cellular responses to pH alterations in both physiological (taste, pain) and pathological settings (ischemia and cancers). Furthermore, these authors present a broad spectrum of investigative approaches to cellular response to acidosis in a in wide variety of human diseases. 168 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Current pharmaceutical and clinical approaches to the treatment of disease suffer from the inherent limitations in the specialization of drugs introduced to physiological systems. The interface of clinical and material sciences has allowed for a broad spectrum of creative approaches with the potential to alleviate these shortcomings. However, the synergy of these disciplines also presents problems in which nascent technology lacks the necessary evaluation within its intended clinical environment. Given the growing potential for materials science to address a number of unanswered therapeutic needs, it remains even more pressing to validate emerging drug delivery technologies in actual clinical environments. Drug Delivery: Materials Design and Clinical Perspective addresses the core fundamentals of drug delivery using material science and engineering principles, and then applies this knowledge using prominent examples from both the scientific literature and clinical practice. Each chapter focuses on a specific drug delivery technology, such as controlled-release materials, thin-film materials, or smart materials. Within each chapter, an initial section on 'Engineering Concepts' reviews the relevant fundamental principles that guide rational design. The following section on 'Materials Design' discusses how the design process applies engineering concepts for use in physiological systems. A third section on 'Implementation' discusses current approaches in the literature which have demonstrated effective drug delivery in controlled environments. Finally, each chapter contains several sections on 'Clinical Applications' which describe the validity of materials approaches from a clinical perspective; these sections review the safety and efficacy of drug delivery systems for specific, compelling medical applications. The book thereby bridges materials science with clinical medicine, and provides the reader with a bench-to-bedside view of novel drug delivery systems. Provides a comprehensive description of drug delivery systems from a materials perspective Includes a wide-ranging discussion of clinical applications of drug delivery systems Presents separate chapters on controlled release materials, thin film materials, self-microemulsifying materials, smart materials, etc. Covers fundamental engineering principles, rational materials design, implementation testing, and clinical applications for each material type 376 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents a new approach to the analysis of networks, which emphasizes how one can compress a network while preserving all information relative to the network's spectrum. Besides these compression techniques, the authors introduce a number of other isospectral transformations and demonstrate how, together, these methods can be applied to gain new results in a number of areas. This includes the stability of time-delayed and non time-delayed dynamical networks, eigenvalue estimation, pseudospectra analysis and the estimation of survival probabilities in open dynamical systems. The theory of isospectral transformations, developed in this text, can be readily applied in any area that involves the analysis of multidimensional systems and is especially applicable to the analysis of network dynamics. This book will be of interest to Mathematicians, Physicists, Biologists, Engineers and to anyone who has an interest in the dynamics of networks. 192 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The second edition of Solar System Astrophysics: Background Science and the Inner Solar System provides new insights into the burgeoning field of planetary astronomy. As in the first edition, this volume begins with a rigorous treatment of coordinate frames, basic positional astronomy, and the celestial mechanics of two and restricted three body system problems. Perturbations are treated in the same way, with clear step-by-step derivations. Then the Earth's gravitational potential field and the Earth-Moon system are discussed, and the exposition turns to radiation properties with a chapter on the Sun. The exposition of the physical properties of the Moon and the terrestrial planets are greatly expanded, with much new information highlighted on the Moon, Mercury, Venus, and Mars.All of the material is presented within a framework of historical importance. This book and its sister volume, Solar System Astrophysics: Background Science and the Inner Solar system, are pedagogically well written, providing clearly illustrated explanations, for example, of such topics as the numerical integration of the Adams-Williamson equation, the equations of state in planetary interiors and atmospheres, Maxwell's equations as applied to planetary ionospheres and magnetospheres, and the physics and chemistry of the Habitable Zone in planetary systems.Together, the volumes form a comprehensive text for any university course that aims to deal with all aspects of solar and extra-solar planetary systems. They will appeal separately to the intellectually curious who would like to know how just how far our knowledge of the solar system has progressed in recent years. 356 pp. Englisch.

Taschenbuch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book covers the issues of monitoring, failure localization, and restoration in the Internet optical backbone, and focuses on the progress of state-of-the-art in both industry standard and academic research. The authors summarize, categorize, and analyze the developed technology in the context of Internet fault management and failure recovery under the Generalized Multi-Protocol Label Switching (GMPLS), via both aspects of network operations and theories. 220 pp. Englisch.