9780306420900

Book Description: Book Condition: Acceptable. Book Condition: Acceptable * All orders are processed and shipped from Las Vegas Nevada USA *. Bookseller Inventory # 97803064209005.0

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Book Description: Book Condition: Very Good. Book Condition: Very Good * All orders are processed and shipped from Las Vegas Nevada USA *. Bookseller Inventory # 97803064209003.0

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Book Description: Plenum Press, New York, 1985. Hardcover. Book Condition: Very Good Ex-Library Cond Book. 8vo - over 7¾" - 9¾" tall. 394 pgs. White boards. This volume, the fourth in the series "The Prostaglandin System", contains most of the presentations at the International School of Pharmacology on "Drugs Effecting Leukotrienes and other Eicosanoid pathways" held in Erice, Sicily, at the "Ettore Majorana Center" on 9-20 September 1984. CHAPTER TITLES: introduction; measurement of thromboxane production in vivo: metabolic and analytical aspects; high pressure liquid chromatography-125J-ria, a sensitive and specific prostaglandin assay; enzyme immunoassays of icosanoids using acetylcholinesterase; syntheses and biological effects of leukotrienes and analogs; pharmacologic modulation of leukotriene biosynthesis by incorporation of alternative unsaturated fatty acids (20:5) and 22:6); studies with inhibitors of leukotriene biosynthesis with special referenc eto piriprost (u-60,257); pulmonary and vascular efffects of Leukotriene, involvement in asthma and inflammation; modulation of the release of leukotrienes and prostaglandins and of their functional effects in human and guinea-pig lung parenchyma; comparative effects of leukotrienes in respiratory tissue of various species; the effects of low-dose aspirin and selective inhibitors of thromboxane-synthase on eicosanoid production in man; manipulation of pro- and antiaggregating prostaglandsin: new antithrombotic activities; flavonoids--lipoxygenases--platelet aggregation; transformation of 15-hydroperoxyeicosapentaenoic acid into mono- and dihydroxyeicosapentaenoic acids by human platelets; metabolism of arachidonic acid by 12- and 15-lipoxygenases in human platelets and polymorphonuclear leukocytes; epoxidation of arachidonic acid and prostacyclin in the kidney; the effect of 9 a-fluorohydrocortisone on the urinary excretion of 6-keto-pgf1 in man; prostacyclin in therapy of vascular disease; ltc4 induces hyperreactivity of the isolated vascular tissue to histamine, serotonin and norepinephrine; evidence for a thromboxane antagonist in selected in vitro and invivo systems; precursor-product relationship in vascular eicosanoid formation after manipulation of dietary fatty acids in experimental animals; formation of leukotrienes and other eicosanoids in the gastrointestinal tract and effect of drugs; role of eicosanoids in the pathogenesis of inflammatory bowel diseases; inhibition of 5'lipoxygenase: relevance to inflammation; the role of glucocorticoid-induced phospholipase inhibitory proteins; formation and oxidative degradation of leukotrienes by eosinophils and neutrophils; eicosanoids and cancer; stimulated human colonic synthesis of arachidonate lipoxygenase and cyclo-oxygenase products by laxatives; and correlation between K+ fluxes and the arachidonic acid cascade in human leukocyte stimulated with a-23187 or melittin. Usual library markings but otherwise clean and tight. Corners lightly bumped. Book. Bookseller Inventory # B026922

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Book Description: Book Condition: Very Good. Clean, tight. Bookseller Inventory # HH-012-20-1283301

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