The Pulitzer Prize winning "Arrowsmith" (an award Lewis refused to accept) recounts the story of a doctor who is forced to give up his trade for reasons ranging from public ignorance to the publicity-mindedness of a great foundation, and becomes an isolated seeker of scientific truth. Introduction by E.L. Doctorow.
"Intellectually..., ARROWSMITH leaves Mr. Lewis about where he was. And that means it leaves him in a unique and unassailable position, with all his possibilities intact....Artistically, ARROWSMITH is an authentic step forward. The novel is full of passages of a quite noble felicity and the old skill in presenting character through dialogue never fails."
Henry L. Stuart, New York Times Book Review, 03/08/1925
"Perhaps the novel's greatest strength is its veracity of detail about a life in medicine, from the conflicts that arise between commerce and altruism to the design of scientific experiments...While hilariously assaulting the babbitry of the medical profession, Lewis captures the absolute passion for discovery required of a successful scientist."
Howard Markel, New York Times Book Review, 09/24/2000