From the Publisher:
A ready reference describes analyses performed in a variety of areas and how they are instrumental in solving some of the complex scientific problems relative to drugs, food safety, pharmaceuticals, air, food, water, and the environment. Provides a reference to methodologies and forensics. Aids in selecting the best method for determining the mechanism of action, disposition, and toxic properties of chemicals.
From the Inside Flap:
Ultratrace Analysis of Pharmaceuticals and Other Compounds of Interest is a highly useful reference to the many specialized and complicated analyses performed below trace level. The methodologies provided in this manual make it an invaluable research tool for in-depth studies of action, dispositions, and toxic properties of chemicals. It is also an excellent aid in determining the safety of our food, water and environment, and the modes of action of drugs. The book brings together a multitude of applications from science and industry. It includes many specialized methods of analysis performed in clinical, forensic, environmental, and food chemistry research and development. In the first of its two main sections, this important work covers commonly used analytical methods, such as derivatization chromatography, atomic spectrometry, liquid chromatography, including LC/MS and modern thin-layer chromatography. Since immunoassays provide selective applications, they are included in a special chapter on the analysis of drugs and their metabolites. The second section focuses on the applications of ultratrace analyses—addressing the growing concern for the purity of pharmaceutical compounds and excipients. Then, the book shows how ultratrace analyses assist the performance of metabolic and toxicological studies. The last three chapters reveal the importance and applications of these analyses in the use and abuse of drugs in animals and humans. Analytical chemists and scientists who use ultratrace analyses in food, pharmaceutical, and environmental research will find this book vital to their work. It is also relevant and important to technicians and researchers in the forensic field and any area that calls for information at the submicro level.
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