An indispensable guide to an emerging technology, this unique book introduces detailed methods for the construction, screening, and use of DNA sequences cloned into yeast artificial chromosome (YAC) vectors and the applications of YACs to gene hunting. Also covered are the reconstruction of large genes and the analysis of YACs by insertion back into mammalian cells--a method that may lead to the therapeutic use of YAC clones. The methods described are drawn from work on human DNA, but are universal to yeast artificial chromosomes used in other organisms. YAC Libraries is the third volume in the UWBC Biotechnical Resource Series with Dr. Richard Burgess, Director of the University of Wisconsin Biotechnology center, as Series Editor. The series is dedicated to providing practical guidance to researchers exploring new technologies and services.
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David L. Nelson, Institute for Molecular Genetics, Baylor College of Medicine. Bernard Brownstein, Center for Genetics in Medicine, Washington University School of Medicine.
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Book Description Oxford University Press, 1993. Paperback. Book Condition: Good. Item may show signs of shelf wear. Pages may include limited notes and highlighting. Includes supplemental or companion materials if applicable. Access codes may or may not work. Connecting readers since 1972. Customer service is our top priority. Bookseller Inventory # mon0000107258
Book Description Book Condition: Good. This item is in good condition. All pages and covers are readable. There are no stains or tears. Dust jacket is present if applicable. May contain small amounts of writing and/or highlighting. Spine and cover may show signs of wear. May not contain supplementary items. We ship within 1 business day. Bookseller Inventory # 34FCXK000SYO
Book Description Oxford University Press, USA, 1993. Paperback. Book Condition: Used: Good. Bookseller Inventory # SONG0716770148
Book Description Oxford University Press, 1993. Paperback. Book Condition: Good. Good condition, some are ex-library and can have markings. Bookseller Inventory # GD-041-84-4554704