Protein and Peptide Analysis by LC-MS: Experimental Strategies (RSC Chromatography Monographs, Volume 15) - Hardcover

Hardcover

ISBN 10: 1849731829 ISBN 13: 9781849731829

Publisher: Royal Society of Chemistry, 2011

Synopsis

This book is the first example in presenting LC-MS strategies for the analysis of peptides and proteins with detailed information and hints about the needs and problems described from experts on-the-job. The best advantage is -for sure- the practical insight of experienced analysts into their novel protein analysis techniques. Readers starting in 'Proteomics' should be able to repeat each experiment with own equipment and own protein samples, like clean-up, direct protein analysis, after (online) digest, with modifications and others. Furthermore, the reader will learn more about strategies in protein analysis, like quantitative analysis, industrial standards, functional analysis and more.

About this title

About the Author:

Thomas Letzel is associate professor for analytical chemistry and bioanalysis at the Wissenschaftszentrum Weihenstephan (WZW) located at the TUM (Technische Universitõt M³nchen), Germany. He obtained his PhD in Chemistry with studies about soot aerosols and environmental analysis at the Chair for Analytical Chemistry of TUM. After a postdoc time in Amsterdam, The Netherlands, at the VU Amsterdam with topics in pharmaceutical and enzymatic analysis, he came back to TUM and was employed as a scientist, leading a new analytical research group with focus on bioanalysis. In latter position he got his Habilitation. He developed and established mass spectrometric techniques coupled with modern liquid phase solution techniques in enzymology, studying noncovalent complexes and observing molecular fingerprints. His research of novel mass spectrometric techniques comprises the identification and characterization of organic molecules in applications of biological, environmental, pharmaceutical, food, plant and nutrition sources.

Review:

This book is the first its kind of detailed information by LC-MS strategies scanner Peptides and proteins.the most intriguing Advantage is Security of practical Insight of the experienced experts (portal.mytum.de/pressestelle/tum_mit/2011nr4/58.pdf/download TUM campus 4/11)

I would regard the book under review here not as a textbook to recommend to students but rather as a source of information for graduate students, technical personnel, and scientists. For a graduate student involved with LC-MS for three years it may be worth having the book on the shelf. It is a valuable means of getting started in proteomicsthe book has earned its place on the bench in an interdisciplinary life-science environment. (Simone Konig DOl 10.1 007/s10337 -012-2208-6)

About this edition

• Publisher: Royal Society of Chemistry
• Publication date: 2011
• ISBN 10: 1849731829
• ISBN 13: 9781849731829
• Binding: Hardcover
• Edition number: 1
• Number of pages: 194
• Editor: Letzel Thomas