Phosphodiesterases as Drug Targets (Handbook of Experimental Pharmacology, 204) - Hardcover
Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors.
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- PublisherSpringer
- Publication date2011
- ISBN 10 3642179681
- ISBN 13 9783642179686
- BindingHardcover
- Number of pages540
- EditorFrancis Sharron H., Conti Marco, Houslay Miles D.
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Phosphodiesterases as Drug Targets
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Book Description Gebunden. Condition: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. provides a summary of the major concepts related to the design and use of PDE inhibitorsdescribes exciting ideas and developments that are currently emerging in this dynamic and important fieldwritten by leading authorities in the fieldCyclic nucleotide. Seller Inventory # 5051601
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Phosphodiesterases as Drug Targets
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Book Description Buch. Condition: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors. 540 pp. Englisch. Seller Inventory # 9783642179686
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Phosphodiesterases as Drug Targets
Published by
Springer Berlin Heidelberg
(2011)
ISBN 10: 3642179681
ISBN 13: 9783642179686
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Hardcover
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Book Description Buch. Condition: Neu. Druck auf Anfrage Neuware - Printed after ordering - Cyclic nucleotide phosphodiesterases (PDEs) are promising targets for pharmacological intervention. Multiple PDE genes, isoform diversity, selective expression and compartmentation of the isoforms, and an array of conformations of PDE proteins are properties that challenge development of drugs that selectively target this class of enzymes. Novel characteristics of PDEs are viewed as unique opportunities to increase specificity and selectivity when designing novel compounds for certain therapeutic indications. This chapter provides a summary of the major concepts related to the design and use of PDE inhibitors. Seller Inventory # 9783642179686
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