Fetology: Diagnosis and Management of the Fetal Patient, Second Edition

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9780071442015: Fetology: Diagnosis and Management of the Fetal Patient, Second Edition

The first book to synthesize relevant, critically reviewed data for application to the diagnosis and treatment of prenatal patients? updated and in full color

A Doody's Core Title for 2011!

5 STAR DOODY'S REVIEW!
"The book is comprehensive, concise, well illustrated, and an extremely valuable resource for perinatal healthcare providers....This book has rapidly become a go-to reference in the perinatal field and this new edition confirms its place as the gold standard in the field. Perinatologists will find this to be an essential part of their library. As more obstetric practitioners do investigative sonographic procedures in their offices, this book will be a valuable resource for them as well. The new edition is overdue and most welcome."--Doody's Review Service

"This invaluable up-to-date reference is a must have guide especially in non-tertiary care centers where the various experts may not be readily available to further guide the family and plan the rest of the antepartum, peripartum and postpartum care."--Center for Advanced Fetal Care Newsletter

Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis?from prenatal management to long-term outcome?for an affected child. Here, you’ll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality?and present them with a coordinated therapeutic plan.

Features

  • NEW! Full-color design
  • NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome
  • NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy
  • NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology
  • NEW! Key Points open each chapter, providing rapid review of a particular condition
  • Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information
  • Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more
  • Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research

"synopsis" may belong to another edition of this title.

About the Author:

Diana W. Bianchi, MD
Natalie V. Zucker Professor of Pediatrics, Obstetrics, and Gynecology
Tufts University School of Medicine
Vice Chair for Research and Academic Affairs
Department of Pediatrics
Floating Hospital for Children at Tufts Medical Center
Boston, MA
Timothy M. Crombleholme, MD
Richard G and Geralyn Azizkhan Chair in Pediatric Surgery
Professor of Surgery, Pediatrics (Molecular and Developmental Biology), and Obstetrics and Gynecology
Director, Fetal Care Center of Cincinnati
University of Cincinnati College of Medicine
Associate Director of the Cincinnati Children’s Research Foundation
Cincinnati Children’s Hospital Medical Center
Cincinnati, OH
Mary E. D'Alton, MD
Willard c. Rappelye Professor of Obstetrics and Gynecology
Chair, Department of Obstetrics and Gynecology
Director, Obstetrics and Gynecology Services
Columbia University Medical Center
Sloane Hospital for Women
New York Presbyterian Hospital
Columbia University, College of Physicians and Surgeons
New York, NY
Fergal D. Malone, MD
Professor and Chairman
Department of Obstetrics and Gynecology
Vice Dean
School of Medicine
Royal College of Surgeons in Ireland
The Rotunda Hospital
Dublin, Ireland

From The New England Journal of Medicine:

Forty years ago it made sense to link obstetrics with gynecology because both dealt exclusively with the care of women, pregnant or not. In the 1960s, research began to focus on the hitherto unexplored world of the developing fetus, and the technological explosion of the mid-1970s made it possible for the first time to visualize the fetus throughout gestation and to monitor its development. Direct and indirect tests of fetal well-being were subsequently developed and led to fetal therapy; the first report of intraperitoneal fetal red-cell transfusion for Rh isoimmunization appeared in 1963.

Simultaneously, advances in knowledge about genetics and related technology raised the possibility of genetic evaluation of the fetus. The first report of successful karyotyping of amniocytes appeared in 1966, followed by the first report of genetic amniocentesis in 1970. By the mid-1970s, the fetus had become a full-fledged patient, and obstetrics had become a complicated specialty -- so much so that in 1974 the first board-certification examination was given in the subspecialty of maternal-fetal medicine, in recognition of the tremendous body of knowledge in this area. Obstetricians now care for two patients, the pregnant woman and her fetus, and are expected to diagnose abnormalities accurately and to provide therapy appropriate to both.

To provide such services, the obstetrician struggling to keep up with the explosion of information and technology has had to refer to sonography textbooks to confirm the correct interpretation of the ultrasound image, a variety of references in the area of genetics to pull together the constantly changing data regarding the possibility of prenatal genetic diagnosis and the implications of any identified abnormality, and the literature on maternal-fetal medicine and pediatric surgery to keep abreast of the dramatic new fetal therapies currently offered or being investigated.

In many centers, the overwrought patient is referred to specialists in radiology, genetics, maternal-fetal medicine, pediatric surgery, and other fields to obtain the comprehensive information and services required for many fetal abnormalities. However, when confronted with a fetal anomaly, even these subspecialists sometimes find it difficult to compile the most recent data, present a balanced and thorough review of the issues in a way that is meaningful to the patient, and provide appropriate therapy.

What was desperately needed was a single source of relevant, critically reviewed data, along with therapeutic guidance. Fetology is such a resource. The practitioner who has identified a fetal abnormality can turn to the appropriate chapter in this book and find all the information needed to make the diagnosis, counsel the patient, and provide therapy. Since ultrasonography provides the first and possibly the best opportunity to evaluate the fetus, the topics are organized according to organ system, and the anomalies of each system that are commonly detected by sonography are presented alphabetically. Each chapter is thus devoted to a single anomaly -- for example, encephalocele -- and includes a description of the anomaly, its incidence, the characteristic sonographic findings, the differential diagnoses, the antenatal natural history, the best treatment during pregnancy (including possible fetal therapies), the appropriate treatment of the newborn, the expected long-term outcome, the genetic features of the anomaly, and the risk of recurrence. Each of these sections contains a succinct critical review of the relevant literature and the reasoning behind any recommendations, as well as a frank discussion of the gaps in our knowledge.

The three authors of Fetology represent the subspecialties of genetics, pediatric surgery, and maternal-fetal medicine, which probably accounts for the well-balanced approach to each anomaly and the fact that the information in all the subsections of each chapter is equally strong. The authors, all recognized experts in their fields, are the very best type of consultants; they combine an academic approach to the analysis of data and an objective review of controversial areas with knowledge gained firsthand by caring for patients. Thus, the reader learns both what the research says and what these experienced clinicians would do. An added bonus is that the book is written clearly, in one voice, and follows Einstein's dictum that "things should be made as simple as possible, but not any simpler."

As an example of the book's approach to anomalies, consider the chapter on choroid-plexus cysts. These cysts are a source of distress among patients and physicians because they can be recognized even by inexperienced sonographers and they occur commonly in both normal and abnormal fetuses. The patient who is referred for the evaluation of such cysts in her fetus is usually tearful and anxious, in large part because of the referring clinician's inability to provide counseling regarding their significance. The radiologist, obstetrician, or specialist in maternal-fetal medicine who then evaluates the fetus turns to the literature and finds that it is full of case reports and small series accompanied by a wide variety of disparate conclusions about the clinical significance of choroid-plexus cysts and their management. The clinician who turns to Fetology, however, will learn how choroid-plexus cysts form, the history of their prenatal diagnosis, the source of the concern that they indicate fetal trisomy 18, their natural history, and a logical approach to management. The rationale behind the recommendations is provided, including a review of the risk of fetal trisomy 18 in relation to maternal age, an explanation of how to alter this a priori risk with a likelihood ratio (derived from the association of aneuploidy with choroid-plexus cysts) to compute a posterior probability, and a discussion of how to include the presence or absence of other structural abnormalities in the calculation. By the end of this chapter, readers have learned the best approach to the diagnosis and management of fetal choroid-plexus cysts, have reviewed the relevant literature and some valuable statistical principles, and, probably most important, have read such a clear presentation of the issues that they will feel comfortable explaining them to patients.

Every chapter contains a wealth of information compiled in a way that most readers will find novel and many interesting tidbits that will be new even to experienced clinicians. The chapter on neural-tube defects, for example, includes the signs and symptoms of hindbrain dysfunction in the neonate with a neural-tube defect and the indications for surgical decompression, along with pearls such as the fact that surgical treatment is complicated by the high frequency of latex allergy in these infants (although this fact is unreferenced). The chapter on nonimmune hydrops includes the most complete differential-diagnosis list I have ever seen. Even the rarest entities, such as hemifacial microsomia and tetrasomy 12p, are presented in the same complete manner. Think of an entity that has caused frustration because it is not fully covered in any of the standard textbooks, and it is here. There are chapters on iniencephaly, agenesis of the corpus callosum, bronchogenic cysts, pentalogy of Cantrell, arthrogryposis, and retinoblastoma, to name just a few. The ultrasound images are excellent, and the other illustrations are very good.

My only quibbles are minor and mostly confined to the first two chapters, which provide an overview of prenatal imaging and prenatal diagnostic procedures. These chapters do not present as balanced a view of the topics as that found in the rest of the book, and they contain more declarative but unreferenced statements than the other chapters, but this probably results from the need for brevity. For example, one of these chapters states that amniocentesis is offered when triple-marker screening reveals a risk of Down's syndrome that is higher than 1 in 270, when, actually, different laboratories use different cutoffs -- for example, 1 in 200 or 1 in 365. This variation has been a source of confusion for clinicians and patients and could have been explained here. Some of these statements are outdated. The authors claim, for instance, that percutaneous umbilical-cord sampling is required to determine the fetal blood type, although the fetal Rh type can now be determined by analysis of amniocytes obtained by amniocentesis; the authors also say that percutaneous umbilical-cord sampling at term is required for management of idiopathic thrombocytopenic purpura, although most authorities, including the American College of Obstetricians and Gynecologists, now acknowledge that such sampling is unnecessary. The chapter on anencephaly says that termination should be offered because this condition "carries an increased medical risk to the mother," although no data are provided to support this statement. There are also a few editing errors in these chapters. However, these are minor problems and do not detract from the excellent information in the rest of the book; the reader who needs more information on the topics covered in these introductory chapters can make use of the fine reference list offered in each one.

In summary, this is a well-written, easy-to-use reference book that fills a well-defined need. It is interesting enough to read straight through but well organized enough to read a chapter at a time. Those of us who have had the experience of spending hours trying to find the latest diagnostic and therapeutic information on a relatively rare anomaly, only to come up short, will be grateful that this book is on our shelves.

Katherine D. Wenstrom, M.D.
Copyright 2001 Massachusetts Medical Society. All rights reserved. The New England Journal of Medicine is a registered trademark of the MMS.

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Book Description McGraw-Hill Education - Europe, United States, 2010. Hardback. Book Condition: New. 2nd Revised edition. 279 x 224 mm. Language: English . Brand New Book. The first book to synthesize relevant, critically reviewed data for application to the diagnosis and treatment of prenatal patients- updated and in full color A Doody s Core Title for 2011! 5 STAR DOODY S REVIEW! The book is comprehensive, concise, well illustrated, and an extremely valuable resource for perinatal healthcare providers.This book has rapidly become a go-to reference in the perinatal field and this new edition confirms its place as the gold standard in the field. Perinatologists will find this to be an essential part of their library. As more obstetric practitioners do investigative sonographic procedures in their offices, this book will be a valuable resource for them as well. The new edition is overdue and most welcome. --Doody s Review Service This invaluable up-to-date reference is a must have guide especiallyin non-tertiary care centers where the various experts may not be readily available tofurther guide the family and plan the rest of the antepartum, peripartum and postpartum care. --Center for Advanced Fetal Care Newsletter Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis-from prenatal management to long-term outcome-for an affected child. Here, you ll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality-and present them with a coordinated therapeutic plan. Features NEW! Full-color design NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology NEW!Key Points open each chapter, providing rapid review of a particular condition Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research. Bookseller Inventory # AA39780071442015

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Book Description Mcgraw Hill Medical, 2005. Gebundene Ausgabe. Book Condition: Neu. Neu Neuware, Importqualität, auf Lager, SCHNELLVERSAND mit dpd - The first book to synthesize relevant, critically reviewed data for application to the diagnosis and treatment of prenatal patients- updated and in full color A Doody's Core Title for 2011! 5 STAR DOODY'S REVIEW! 'The book is comprehensive, concise, well illustrated, and an extremely valuable resource for perinatal healthcare providers.This book has rapidly become a go-to reference in the perinatal field and this new edition confirms its place as the gold standard in the field. Perinatologists will find this to be an essential part of their library. As more obstetric practitioners do investigative sonographic procedures in their offices, this book will be a valuable resource for them as well. The new edition is overdue and most welcome.'-- Doody's Review Service 'This invaluable up-to-date reference is a must have guide especiallyin non-tertiary care centers where the various experts may not be readily available tofurther guide the family and plan the rest of the antepartum, peripartum and postpartum care.'-- Center for Advanced Fetal Care Newsletter Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis-from prenatal management to long-term outcome-for an affected child. Here, you'll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality-and present them with a coordinated therapeutic plan. Features NEW! Full-color design NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology NEW! Key Points open each chapter, providing rapid review of a particular condition Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research 1004 pp. Englisch. Bookseller Inventory # INF1000309516

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Book Description McGraw-Hill Education - Europe, United States, 2010. Hardback. Book Condition: New. 2nd Revised edition. 279 x 224 mm. Language: English . Brand New Book. The first book to synthesize relevant, critically reviewed data for application to the diagnosis and treatment of prenatal patients- updated and in full color A Doody s Core Title for 2011! 5 STAR DOODY S REVIEW! The book is comprehensive, concise, well illustrated, and an extremely valuable resource for perinatal healthcare providers.This book has rapidly become a go-to reference in the perinatal field and this new edition confirms its place as the gold standard in the field. Perinatologists will find this to be an essential part of their library. As more obstetric practitioners do investigative sonographic procedures in their offices, this book will be a valuable resource for them as well. The new edition is overdue and most welcome. --Doody s Review Service This invaluable up-to-date reference is a must have guide especiallyin non-tertiary care centers where the various experts may not be readily available tofurther guide the family and plan the rest of the antepartum, peripartum and postpartum care. --Center for Advanced Fetal Care Newsletter Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis-from prenatal management to long-term outcome-for an affected child. Here, you ll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality-and present them with a coordinated therapeutic plan. Features NEW! Full-color design NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology NEW!Key Points open each chapter, providing rapid review of a particular condition Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research. Bookseller Inventory # AA39780071442015

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Book Description McGraw-Hill Medical/Jaypee Brothers Medical Publishers, 2010. Hardcover. Book Condition: New. 2nd edition. Fetology: Diagnosis and Management of the Fetal Patient offers a cross-disciplinary approach that goes beyond the traditional boundaries of obstetrics, pediatrics, and surgery to help you effectively diagnose and treat fetal patients. Fetology considers the full implications of a fetal sonographic or chromosomal diagnosis?from prenatal management to long-term outcome?for an affected child. Here, you?ll find all the insights you need to answer the questions of parents faced with a diagnosis of a fetal abnormality?and present them with a coordinated therapeutic plan. Features NEW! Full-color design NEW! Five new chapters on Adrenal Masses, Abdominal Cysts, Overgrowth, Mosaic Trisomy, and DiGeorge Syndrome NEW! Chapters summarizing contemporary approaches to first and second trimester screening for aneuploidy NEW! 3D ultrasound and MRI images: over 450 images clearly illustrate the diagnosis of anomalies with the latest, most precise imaging technology NEW! Key Points open each chapter, providing rapid review of a particular condition Highlighted treatment/management guidelines deliver quick access to practical, what-to-do information Each chapter, which covers a single anomaly, includes description of the medical condition, incidence, characteristic sonographic findings, differential diagnosis, best treatment during pregnancy, treatment of the newborn, expected outcome, and more Addresses gaps in our knowledge that highlight unmet clinical needs and areas for future research Table of contents Prefaces Acknowledgments Part I: Introduction Chapter 1: Prenatal Imaging Chapter 2: First Trimester Screening for Aneuploidy Chapter 3: Second Trimester Screening for Aneuploidy Chapter 4: Prenatal Diagnostic Procedures Chapter 5: Fetal Intervention Part II: Management of Fetal Conditions Diagnosed by Sonography Section A: Central Nervous System Chapter 6: Agenesis of the Corpus Callosum Chapter 7: Anencephaly Chapter 8: Arachnoid Cyst Chapter 9: Cerebral Calcifications Chapter 10: Craniosynostosis Chapter 11: Dandy-Walker Malformation and Variants Chapter 12: Encephalocele Chapter 13: Exencephaly/Acrania Chapter 14: Holoprosencephaly Chapter 15: Hydranencephaly Chapter 16: Hydrocephalus Chapter 17: Intracranial Hemorrhage Chapter 18: Macrocephaly Chapter 19: Myelomeningocele Chapter 20: Microcephaly Chapter 21: Porencephaly Chapter 22: Vein of Galen Aneurysm Section B: Craniofacial Chapter 23: Cleft Lip and Cleft Palate Chapter 24: Hemifacial Microsomia Chapter 25: Hypertelorism Chapter 26: Hypotelorism Chapter 27: Macroglossia Chapter 28: Micrognathia and Agnathia Chapter 29: Microphthalmia/Anophthalmia Section C: Neck Chapter 30: Congenital High Airway Obstruction Syndrome Chapter 31: Cystic Hygroma in Early Pregnancy Chapter 32: Cystic Hygroma in Late Pregnancy Chapter 33: Goiter Section D: Thoracic Chapter 34: Bronchopulmonary Sequestration Chapter 35: Cystic Adenomatoid Malformation Chapter 36: Other Cystic Lesions of the Chest Chapter 37: Congenital Diaphragmatic Hernia Chapter 38: Hydrothorax Chapter 39: Pulmonary Agenesis Chapter 40: Esophageal Atresia and Tracheoesophageal Fistula Section E: Cardiovascular Chapter 41: Tachyarrhythmias Chapter 42: Bradyarrhythmias Chapter 43: Atrial Septal Defects Chapter 44: Ventricular Septal Defects Chapter 45: Atrioventricular Canal Defect Chapter 46: Ebstein Anomaly Chapter 47: Hypoplastic Right Ventricle Chapter 48: Hypoplastic Left Ventricle Chapter 49: Pulmonary Stenosis and Atresia Chapter 50: Aortic Stenosis Chapter 51: Coarctation of the Aorta Chapter 52: Tetraology of Fallot Chapter 53: Double Outlet Right Ventricle Chapter 54: Truncus Arteriosus Chapter 55: Transposition of Great Arteries Chapter 56: Heterotaxy Syndrome Chapter 57: Cardiomyopathy Printed Pages: 1056. Bookseller Inventory # 43016

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