Molecular Neuropharmacology: A Foundation for Clinical Neuroscience, Third Edition - Softcover

Nestler, Eric; Hyman, Steven; Malenka, Robert

Softcover

ISBN 10: 0071827692 ISBN 13: 9780071827690

Publisher: McGraw Hill / Medical, 2015

Synopsis

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GAIN A COMPLETE UNDERSTANDING OF NERVOUS SYSTEM FUNCTION AND ITS RELATIONSHIP TO HUMAN NEUROLOGIC DISORDERS

Molecular Neuropharmacology first reviews the fundamental biochemistry of the functioning nervous system and then describes how nerve cells communicate with one another through numerous types of neurotransmitters involving amino acids, monoamines, neuropeptides, and neurotrophic factors, among several others.

The neuropharmacology and neural circuits that underlie complex behaviors as well as major neural disorders are also discussed as are the drugs used to treat those conditions. In the final section, the authors use the concepts presented in the first two sections to explainhow irregularities in the biochemistry of neuronal interactions can lead to a wide array of clinical manifestations.

FEATURES

• NEW chapter on neuroinflammation
• All chemical structure illustrations have been redrawn and improved
• Fully updated to reflect the latest breakthroughs and new drugs
• The most well-written and easily understood work on the subject
• More than 300 full-color illustrations!

About this title

About the Authors

Eric J. Nestler, MD, PhD (New York, NY) Nash Family Professor of Neuroscience; Chairman, Department of Neuroscience and Director of the Mount Sinai Brain Institute, Mount Sinai School of Medicine.
Steven E. Hyman, MD (Cambridge, MA) Director, Stanley Center for Psychiatric Research, Broad Institute; Distinguished Service Professor of Stem Cell and Regenerative Biology Harvard University.
Robert C. Malenka, MD, PhD (Palo Alto, CA) Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences; Director, Nancy Friend Pritzker Laboratory, Stanford University School of Medicine.
David M. Holtzman, MD (St. Louis, MO) Andrew B. and Gretchen P. Jones Professor of Neurology Charlotte and Paul Hagemann Professor of Neurology Chairman, Department of Neurology Professor, Molecular Biology and Pharmacology Washington University School of Medicine in St. Louis Neurologist-in-Chief, Barnes-Jewish Hospital

Steven E. Hyman, MD is Provost of Harvard University and Professor of Neurobiology at Harvard Medical School, Boston, MA. From 1996 to 2001, he served as Director of the National Institute of Mental Health (NIMH), the component of the US National Institutes of Health charged with generating the knowledge needed to understand and treat mental illness. Before serving as Director of NIMH, Dr. Hyman was Professor of Psychiatry at Harvard Medical School, Director of Psychiatry Research at Massachusetts General Hospital , and the first faculty Director of Harvard University's Mind, Brain, and Behavior Initiative. In the laboratory he studied the molecular biology of neurotransmitter action. Dr. Hyman is a member of the Institute of Medicine of the National Academy of Sciences and of the American Academy of Arts and Sciences. He is currently serves as Editor of the Annual Review of Neuroscience. He received his BA from Yale College in 1974 summa cum laude, and his MA from the University of Cambridge in 1976, which he attended as a Mellon fellow studying the history and philosophy of science. He earned his MD from Harvard Medical School in 1980.

Robert C. Malenka, MD, PhD is Pritzker Professor of Psychiatry & Behavioral Sciences at Stanford University, Palo Alto, CA. He is a fellow of the American Academy of Arts and Sciences, a member of the Institute of Medicine of the National Academies and an Associate of the Neurosciences Research Program. He has won several awards including the International Prize in Neuroscience, the Distinguished Alumni Award from Stanford University and the Daniel Efron Award from the American College of Neuropsychopharmacology. A major goal of his laboratory is to elucidate both the specific molecular events that are responsible for the triggering of these various forms of synaptic plasticity and the exact modifications in synaptic proteins that are responsible for the observed, long-lasting changes in synaptic efficacy.

Edition details

• Publisher: McGraw Hill / Medical
• Publication date: 2015
• Language: English
• ISBN 10: 0071827692
• ISBN 13: 9780071827690
• Binding: Paperback
• Edition number: 3
• Number of pages: 544