Encyclopedia of Behavioral Neuroscience, Three-Volume Set, 1- 3

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9780080447322: Encyclopedia of Behavioral Neuroscience, Three-Volume Set, 1- 3

Behavioral Neuroscientists study the behavior of animals and humans and the neurobiological and physiological processes that control it. Behavior is the ultimate function of the nervous system, and the study of it is very multidisciplinary. Disorders of behavior in humans touch millions of people's lives significantly, and it is of paramount importance to understand pathological conditions such as addictions, anxiety, depression, schizophrenia, autism among others, in order to be able to develop new treatment possibilities.

Encyclopedia of Behavioral Neuroscience is the first and only multi-volume reference to comprehensively cover the foundation knowledge in the field. This three volume work is edited by world renowned behavioral neuroscientists George F. Koob, The Scripps Research Institute, Michel Le Moal, Université Bordeaux, and Richard F. Thompson, University of Southern California and written by a premier selection of the leading scientists in their respective fields. Each section is edited by a specialist in the relevant area. The important research in all areas of Behavioral Neuroscience is covered in a total of 210 chapters on topics ranging from neuroethology and learning and memory, to behavioral disorders and psychiatric diseases.

  • The only comprehensive Encyclopedia of Behavioral Neuroscience on the market
  • Addresses all recent advances in the field
  • Written and edited by an international group of leading researchers, truly representative of the behavioral neuroscience community
  • Includes many entries on the advances in our knowledge of the neurobiological basis of complex behavioral, psychiatric, and neurological disorders
  • Richly illustrated in full color
  • Extensively cross referenced to serve as the go-to reference for students and researchers alike
  • The online version features full searching, navigation, and linking functionality
  • An essential resource for libraries serving neuroscientists, psychologists, neuropharmacologists, and psychiatrists

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About the Author:

George F. Koob, Ph.D., is a Professor and Chair of the Committee on the Neurobiology of Addictive Disorders at The Scripps Research Institute and Adjunct Professor in the Departments of Psychology and Psychiatry, and Adjunct Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California, San Diego. Dr. Koob received his Bachelor of Science degree from Pennsylvania State University and his Ph.D. in Behavioral Physiology from The Johns Hopkins University. An authority on addiction and stress, Dr. Koob has published over 670 scientific papers and has received continuous funding for his research from the National Institutes of Health, including the National Institute on Alcohol Abuse and Alcoholism (NIAAA) and the National Institute on Drug Abuse (NIDA). He is Director of the NIAAA Alcohol Research Center at The Scripps Research Institute, Consortium Coordinator for NIAAA's multi-center Integrative Neuroscience Initiative on Alcoholism, and Co-Director of the Pearson Center for Alcoholism and Addiction Research. Dr. Koob is Editor-in-Chief USA for the journal Pharmacology Biochemistry and Behavior and Editor-in-Chief for Journal of Addiction Medicine. He won the Daniel Efron Award for excellence in research from the American College of Neuropsychopharmacology, was honored as a Highly Cited Researcher from the Institute for Scientific Information, was presented with the Distinguished Investigator Award from the Research Society on Alcoholism, and won the Mark Keller Award from NIAAA. He received an honorary doctorate from Pennsylvania State University in 2009.

Dr. Koob's research interests have been directed at the neurobiology of emotion, with a focus on the theoretical constructs of reward and stress. He has made contributions to our understanding of the anatomical connections of the emotional systems and the neurochemistry of emotional function. Dr. Koob has identified afferent and efferent connections of the basal forebrain (extended amygdala) in the region of the nucleus accumbens, bed nucleus of the stria terminalis, and central nucleus of the amygdala in motor activation, reinforcement mechanisms, behavioral responses to stress, drug self-administration, and the neuroadaptation associated with drug dependence.

Dr. Koob also is one of the world's authorities on the neurobiology of drug addiction. He has contributed to our understanding of the neurocircuitry associated with the acute reinforcing effects of drugs of abuse and more recently on the neuroadaptations of these reward circuits associated with the transition to dependence. He has validated key animal models for dependence associated with drugs of abuse and has begun to explore a key role of anti-reward systems in the development of dependence.

Dr. Koob's work with the neurobiology of stress includes the characterization of behavioral functions in the central nervous system for catecholamines, opioid peptides, and corticotropin-releasing factor. Corticotropin-releasing factor, in addition to its classical hormonal functions in the hypothalamic-pituitary-adrenal axis, is also located in extrahypothalamic brain structures and may have an important role in brain emotional function. Recent use of specific corticotropin-releasing factor antagonists suggests that endogenous brain corticotropin-releasing factor may be involved in specific behavioral responses to stress, the psychopathology of anxiety and affective disorders, and drug addiction. Dr. Koob also has characterized functional roles for other stress-related neurotransmitters/neuroregulators such as norepinephrine, vasopressin, hypocretin (orexin), neuropeptide Y, and neuroactive steroids.

Michel Le Moal, M.D., Ph.D, earned his degrees from the University of Bordeaux and University of Grenoble. He was a student at the French school for military physicians and surgeons and then as a navy practitioner he pursued in parallel, his internship and residency in internal medicine, neurology and psychiatry at the Bordeaux Medical School (1954-1968). He earned his medical degree in 1964 and his certification as a child neuropsychiatrist in 1968. He also earned a masters degree in philosophy and psychology (1961, University of Grenoble and Bordeaux) and a masters degree in biological sciences (1962, University of Bordeaux) and finally a Doctorate of Science in 1974 (University of Bordeaux). His academic career developed entirely in Bordeaux, first in child neuropsychiatry (medical school) then in Neuroscience as assistant, associate, full professor (from 1964 to 2004). He was the chairman of the Neurosciences Department (1976-2004), a member of the University Institute of France, and chair of experimental psychopathology. He has been a visiting associate and research fellow at the California Institute of Technology (CALTECH, Pasadena) (1974-1977, Pr J. Olds), The Salk Institute, San Diego (1978-1984, Pr F. E. Bloom, and The Scripps Research Institute, San Diego (1984- present) (Pr F. E. Bloom and Pr G. F. Koob). His research includes the neurobiological bases of stress, addiction, and of adaptive behaviors in general using animal models of psychopathology and experimental psychopathology. He created the François Magendie Neuroscience Institute (1996) in Bordeaux and is still a member of this institution. He is emeritus Professor (University of Bordeaux) and Member of the French Academy of Sciences.

Richard F. Thompson is Keck Professor of Psychology and Biological Sciences at the University of Southern California and was founding Director of the Neuroscience Program at USC (1989-2001). Prior to this he held tenured professorships at the University of Oregon Medical School; University of California, Irvine; Harvard and Stanford. He received his BA degree at Reed College in Portland, OR, his BS and Ph.D. degrees in at the University of Wisconsin, Madison, and did postdoctoral research in Neurophysiology at the University of Wisconsin School of Medicine (with Clinton Woolsey) and the University of Göteburg School of Medicine in Sweden (with Anders Ludberg). His research has focused on neuronal substrates of learning and memory in the mammalian brain; most notably, he (1) elucidated the defining behavioral properties of habituation and sensitization and analyzed the underlying brain processes, and (2) localized and analyzed the essential memory trace for a basic form of association learning and memory in the mammalian brain (to a region in the cerebellum). He has written several texts, published some 470 research papers to date and has received many honors, including election to the National Academy of Sciences, the American Academy of Arts and Sciences, and the American Philosophical Society. He was awarded the Distinguished Scientific Contribution Award from the American Psychological Association, the Warren Medal from the Society of Experimental Psychologists and the Karl Spencer Lashley Award from the American Philosophical Society.

About the Author:

George F. Koob, Ph.D., received his Bachelor of Science degree from Pennsylvania State University and his Ph.D. in Behavioral Physiology from The Johns Hopkins University. He was recently appointed (in 2014) as Director of the National Institute on Alcohol Abuse and Alcoholism (currently on a leave of absence as Professor at The Scripps Research Institute, Adjunct Professor in the Departments of Psychology and Psychiatry at the University of California San Diego, and Adjunct Professor in the Skaggs School of Pharmacy and Pharmaceutical Sciences at the University of California San Diego). As an authority on drug addiction and stress, he has contributed to our understanding of the neurocircuitry associated with the acute reinforcing effects of drugs of abuse and the neuroadaptations of the reward and stress circuits associated with the transition to dependence. Dr. Koob has published over 780 scientific papers. In collaboration with Dr. Michel Le Moal, he wrote the renowned book Neurobiology of Addiction (Elsevier, 2006). He was previously Director of the NIAAA Alcohol Research Center at The Scripps Research Institute, Consortium Coordinator for NIAAA's multi-center Integrative Neuroscience Initiative on Alcoholism, and Co-Director of the Pearson Center for Alcoholism and Addiction Research. He has trained 75 postdoctoral fellows and 11 predoctoral fellows. He is currently Editor-in-Chief of the journal Pharmacology Biochemistry and Behavior and Senior Editor for Journal of Addiction Medicine. Dr. Koob taught for 35 years in the Psychology Department at the University of California San Diego, including courses such as Drugs Addiction and Mental Disorders and Impulse Control Disorders, courses that regularly matriculated 400-500 students each. He also taught Contemporary Topics in Central Nervous System Pharmacology at the Skaggs School of Pharmacy and Pharmaceutical Sciences at UCSD for 9 years.
Dr. Koob's research interests have been directed at the neurobiology of emotion, with a focus on the theoretical constructs of reward and stress. He has made contributions to our understanding of the anatomical connections of the emotional systems and the neurochemistry of emotional function. Dr. Koob has identified afferent and efferent connections of the basal forebrain (extended amygdala) in the region of the nucleus accumbens, bed nucleus of the stria terminalis, and central nucleus of the amygdala in motor activation, reinforcement mechanisms, behavioral responses to stress, drug self-administration, and the neuroadaptation associated with drug dependence.

Dr. Koob also is one of the world's authorities on the neurobiology of drug addiction. He has contributed to our understanding of the neurocircuitry associated with the acute reinforcing effects of drugs of abuse and more recently on the neuroadaptations of these reward circuits associated with the transition to dependence. He has validated key animal models for dependence associated with drugs of abuse and has begun to explore a key role of anti-reward systems in the development of dependence.

Dr. Koob's work with the neurobiology of stress includes the characterization of behavioral functions in the central nervous system for catecholamines, opioid peptides, and corticotropin-releasing factor. Corticotropin-releasing factor, in addition to its classical hormonal functions in the hypothalamic-pituitary-adrenal axis, is also located in extrahypothalamic brain structures and may have an important role in brain emotional function. Recent use of specific corticotropin-releasing factor antagonists suggests that endogenous brain corticotropin-releasing factor may be involved in specific behavioral responses to stress, the psychopathology of anxiety and affective disorders, and drug addiction.

Michel Le Moal, M.D., is Professor Emeritus of Neuroscience at the University of Bordeaux, France. He graduated in Medicine (1962) in Philosophy-Sociology and Natural Science and then Neurology (1967) and Psychiatry (1968). He completed a Doctoral in Science at the University of Bordeaux in 1974. In parallel with his academic life in Bordeaux, he spent time as an Associate Researcher and Professor at Caltech (1974) and at The Salk Institute and The Scripps Research Institute. At both institutions, he worked on dopamine neuron electrophysiology and investigated the roles of brain CRF and dopamine systems in behavior and drug addiction. He research interests concern behavior and adaptive processes, their biological foundations, and experimental psychopathology, a discipline he promoted. The concept of individual vulnerability to behavioral pathologies has been at the center of his working hypothesis. Dr. Le Moal has been the founder and director of several research laboratories at the Centre National de la Recherche Scientifique (CNRS) and Institut National de la Sante et de la Recherche Medicale and finally the Magendie Institute for Neuroscience and Biological Psychiatry in Bordeaux, France. He is an elected Fellow of the French National Academy of Sciences.

Richard F. Thompson is Keck Professor of Psychology and Biological Sciences at the University of Southern California and was founding Director of the Neuroscience Program at USC (1989-2001). Prior to this he held tenured professorships at the University of Oregon Medical School; University of California, Irvine; Harvard and Stanford. He received his BA degree at Reed College in Portland, OR, his BS and Ph.D. degrees in at the University of Wisconsin, Madison, and did postdoctoral research in Neurophysiology at the University of Wisconsin School of Medicine (with Clinton Woolsey) and the University of Göteburg School of Medicine in Sweden (with Anders Ludberg). His research has focused on neuronal substrates of learning and memory in the mammalian brain; most notably, he (1) elucidated the defining behavioral properties of habituation and sensitization and analyzed the underlying brain processes, and (2) localized and analyzed the essential memory trace for a basic form of association learning and memory in the mammalian brain (to a region in the cerebellum). He has written several texts, published some 470 research papers to date and has received many honors, including election to the National Academy of Sciences, the American Academy of Arts and Sciences, and the American Philosophical Society. He was awarded the Distinguished Scientific Contribution Award from the American Psychological Association, the Warren Medal from the Society of Experimental Psychologists and the Karl Spencer Lashley Award from the American Philosophical Society.

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