Advances in Cancer Research (Volume 71) - Hardcover

Hardcover

ISBN 10: 0120066718 ISBN 13: 9780120066711

Publisher: Academic Press, 1997

Synopsis

Volume 71 of Advances in Cancer Research begins with Morgan and Kastan presenting data on the roles of p53 and ATM in cell cycle progression and cell death in response to DNA damage and how this information may lead to targets for improved cancer therapies. Kok et all. Review the methodological advantages and limitations to localizing tumor suppressor genes, especially those on the short arm of chromosome 3. Peltomaki and de la Chapelle describe research on mismatch repair genes and their effects on colorectal cancer. McKenna and Cotter present findings on the functions and failures of apoptosis in the hematopoietic system. Ravitz and Wenner review TGF-B and how it controls and affects cell cycle progression in a variety of cell types. Andrew Simpson presents data on the mutation frequencies of microsatellites in human carcinogenesis. Naor and colleagues present research on a multitude of tumors expressing levels of CD44 and discuss how CD44 may be used as a target for cancer therapy. Luisa Villa discusses various aspects of HPV and the potential clinical use of HPV testing in cervical cancer prevention programs. Last, Disis and Cheever review the studies that define HER-2/neu specific immunity in patients with cancer and the current vaccine strategies for generating specific immunity.

About this title

Review:

Praise for the Serial
"This classic and essential series presents critical overviews on select aspects of both cancer research and the basic underlying sciences."
--AMERICAN SCIENTIST
"Excellent, highly informative, in-depth reviews... expertly written, up-to-date, and well-referenced."
--JOURNAL OF MEDICINAL CHEMISTRY

About this edition

• Publisher: Academic Press
• Publication date: 1997
• ISBN 10: 0120066718
• ISBN 13: 9780120066711
• Binding: Hardcover
• Edition number: 1
• Number of pages: 385
• Editor: Vande Woude George F., Klein George