Signal transduction is one of the most rapidly expanding fields in biomedical research. Written by renowned experts, Intracellular Signal Transduction provides up-to-date reviews on the role of protein phosphorylation cascades, and the structure, regulation, and function of protein kinases and phosphatases. This volume was compiled in honor of Dr. Edwin Krebs' pioneering work in the field of signal transduction which earned him a Nobel Prize. It providesinformation in a variety of areas relating to the biochemistry, cell biology, and pharmacology of the signal transduction process in eukaryotic cells.
Contains current reviews in signal transduction processes in eukaryotic cells
Presents the structure and function of protein kinases and phosphatases
Highlights MAP kinase cascades, tyrosine phosphatases, pharmacology of protein kinases, and cyclic nucleotide phosphodiesterases
July 1996, 310 pp.
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Angus C. Nairn is currently Associate Professor at The Rockefeller University. He has published a large number of papers concerned with the structure and regulation of protein kinases and phosphatases involved in signal transduction, particularly with respect to signalling by calcium.
Recommended not only to pharmacologists but also to all those in related disciplines.
--NATURE
The works do represent an extensive compilation of recent data by outstanding researchers in this area. They are generally scientifically excellent, the bibliographies are good, and the individual reports are clear, concise, and extremely well illustrated.
--H.E. Kaufmann in CHEMOTHERAPY
Superb reading material.
--JOURNAL OF PHARMACEUTICAL SCIENCES
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