Amylin, Volume 52: Physiology and Pharmacology (Advances in Pharmacology)

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9780120329540: Amylin, Volume 52: Physiology and Pharmacology (Advances in Pharmacology)

Amylin deciphers amylin's physiology and reveals previously unrecognized mechanisms fundamental to control body weight and fuel homeostasis. This book also discusses therapeutic utility of amylin as the first new medicine to treat diabetes since insulin.

  • Provides a current comprehensive treatment of amylin the hormone
  • Identifies the majority of amylin's physiologic functions

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Book Description:

The First New Medicine since Insulin for Type-1 Diabetes

From the Back Cover:

By 1994, researchers had progressed toward an understanding of amylin's function, and its therapeutic utility. Amylin's physiology has proven to be surprisingly more simple and elegant than originally conceived. Deciphering amylin's physiology has revealed previously unrecognized mechanisms, fundamental to the control of body weight and fuel homeostasis that are of general physiologic interest, and beyond an interest simply in the peptide itself. The propagation of this knowledge has been hindered by the entanglement of physiologic discovery with the high-risk business of drug development and the challenge of changing the paradigm of diabetes pathophysiology and treatment. Knowledge of amylin's physiologic role is now mature, and is collected and discussed in the current book.

Features:

  • Includes historical background of amylin the peptide
  • Provides a current comprehensive treatment of amylin the hormone
  • Discusses biological actions of amylin and amylinomimetics
  • Therapeutic uses of amylinomimetic drugs

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