The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition

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9780120530755: The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition

The Comprehensive Sourcebook of Bacterial Protein Toxins, Second Edition, provides an up-to-date description of the great advances made in our understanding of the structure, genetics, cellular, and molecular mechanisms of action of bacterial protein toxins over the past decade. This work follows and expands on the first edition (published in 1991), with 70% totally new content and full-color illustrations. Molecular biology, microbiology, immunology, cell biology, protein engineering, structural biochemistry, and clinical research in infectious diseases are brought together to provide a complete overview of the field.

Key Features
* Most up-to-date and comprehensive reference on the subject
* Addresses recent achievements in basic and applied toxin research
* Covers use of bacterial toxins in the development of new vaccines, immunodulators, and therapeutics against cancer and various neurological disorders
* Written by internationally recognized scientists, including Randall Holmes, a recent candidate for presidency of the American Society for Microbiology

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From the Back Cover:

Some of the most damaging toxins known to man - cholera, pertussis, botulinum and tetanus - are produced by bacteria.
The Comprehensive Sourcebook of Bacterial Protein Toxins is the most current and definitive reference work available on the subject.
This major work succeeds and expands on the highly successful Sourcebook of Bacterial Protein Toxins published in 1991, with new and completely revised chapters and colour plate section.
Microbiology, immunology, protein engineering, structural biochemistry, molecular and cell biology and clinical research in infectious diseases are brought together to provide a concise and essential overview for everyone in this and other related fields.
Key Features:
* Addresses recent achievements in basic and applied toxin research
* Covers clinical, pharmacological, therapeutic and epidemiological aspect of bacterial protein toxins
* Use of bacterial toxins in the development of new vaccines and therapeutics against cancer and various neurological diseases
* A-B type toxins (including diptheria, cholera, pertussis and clostridia) bacterial toxins as poisons
* Membrane damaging/pore-forming toxins
* Superantigenic toxins and mitogens
* Edited by two of the most highly regarded authorities in the field

About the Author:

Joseph E. Alouf is Professor of Microbiology at the Pasteur Institute of Lille. He is former Head of the Department of Bacteriology and Mycology at the Pasteur Institute at Paris and Chairman of its Scientific Council. He served as Secretary General of the French Society of Immunology from 1984-1986 and President of the Federation of the European Microbiological Societies from 1989-1992. His 40-year research work relates to the field of bacterial protein toxins and immunology of infectious diseases. He is also the co-editor of several books.

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