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Febrile Seizures is written by the most active researchers and clinicians in epilepsy research today. This book presents the latest developments in this field as well as the current state of knowledge in the following: New imaging tools and emerging data, visualizing effects of febrile seizures on the brain; New genetic methodologies; The use of animal models to permit scientific analysis of the electrophysiology and molecular biology of the seizure.
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Febrile seizures, the most common type of seizures in infants and young children, continue to be the subject of intense interest and controversy among physicians and researchers. But many unanswered questions remain: How do fevers generate seizures; why only in children; why only in SOME children? Are the seizures dangerous? Do they affect intellectual and learning abilities? Do they lead to brain damage? Do they promote epilepsy?
Over the past two decades, a tremendous body of clinical and basic neuroscience research has addressed these questions, but no compendium has brought together the salient information from epidemiological, genetic, clinical, imaging, animal model, and single cell in vitro perspectives. This book spans this remarkable spectrum of approaches to the critical issues of febrile seizures. Each chapter, written by groundbreaking leaders in the field, is pertinent to clinicians who care for children or educate their parents, to those involved in epilepsy research, and to scientists interested in the mechanisms of excitability in the developing brain.
Febrile Seizures is written in an approachable style accessible to those with a general interest in learing on these seizures, their etiology, mechanisms, and consequences.
* First book on febrile seizures in over 20 years!
* Broad spectrum of approaches, from genetic and epidemiological to bench research using animal models and in vitro single-cell patch-clamp methods
* Comprehensive update of the topic, written by world leaders in the field
* Novel and newly discovered information based on up-to the minute methods
* Engaging style, accessible to the clinician, researcher, and educated parent
Tallie Z. Baram, University of California, Irvine, U.S.A.
Shlomo Shinnar, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, U.S.A.
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