This reference book - one of the first of three volumes to launch the "Factsbook" series - contains entries on all CD molecules and all other sequenced molecules expressed on the surface of haematopoietic cells (white and red blood cells). Each entry has a common format, using a minimum amount of text, and contains information on the sequence, expression and Physicochemic properties. The book provides a catalogue of the basic properties of families of proteins and presents gene organization, amino acid sequences, physichochemical properties and biological activity in a straight-forward format.
"synopsis" may belong to another edition of this title.
How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBook series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as "A growing series of excellent manuals' by Molecular Medicine Today, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the new second editions will now keep you up-to-date with the latest advances and provide you with all the new facts at your fingertips. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Second Edition of The Leucocyte Antigen FactsBook has been completely revised, updated and expanded by 65%. It contains over 200 entries on all the molecules specifically expressed on the surface of cells of the haematopoietic system.
Entries provide information on
* Alternative nomenclature
* NEW section on ligands and associated molecules
* Gene organization and chromosomal location
* Protein structure, molecular weights and glycosylation sites
* Amino acid sequences of human proteins
* PIR, SWISSPROT, and EMBL/GenBank accession numbers
* Cellular expression
* Biological function
* Key references
Reviews of the First Edition
"This is an excellent book and a must for all biomedical laboratories with any interest in leukocytes. Of the two copies that I have bought, one has already vanished, a sure sign of an essential volume. The authors must be congratulated on their considerable efforts."
"So well conceived and executed that successive copies sent out for review were almost immediately 'borrowed' by colleagues ... sheer usefulness ... the sort of information you didn't know you needed until someone showed you this book."
"I bought this book immediately after it was published last year as I knew how excellent and indispensable was the first edition... The Second Edition is even more densely packed than the First Edition, containing all the essential and carefully referenced information on leucocyte surface molecules... This is simply a basic book for everybody interested in leucocyte biology and immunology, and there are very few points to criticize."
"...this book simply does not appear to have any weaknesses. Its enormous strength is its clarity and conciseness. There can be very few books that provide so much information in such an attractive and readily accessible way."
"The book is of a timely update and essential reading for all people working in this particular aspect of biomedical science... As a book reviewer, one often spends many tedious hours out of devotion to the editor but on this occasion he has done me proud..."
--JOURNAL OF CLINICAL PATHOLOGY
Praise for the First Edition
"This book is a much needed compendium of information on the leukocyte surface antigens... This is an excellent book and a must for all biomedical laboratories with any interest in leukocytes... The authors must be congratulated on their considerable efforts."
--Andrew McMichael, John Radcliffe Hospital, Oxford, U.K., in NATURE
"The Leucocyte Antigen FactsBook has become an essential tool for the staff of Immunology Today... Written with a strong and engaging narrative tone... It's the sort of information you didn't know you needed until someone showed you this book. Molecular diagrams are provided to help visualize each structure, molecular weights, mode of membrane attachment, protein domain composition and the degree of glycosylation. The tissue distribution is given, along with brief commentaries on structure and function that outline the known features of each molecule."
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Book Description Academic Pr, 1993. Paperback. Book Condition: New. Bookseller Inventory # DADAX0121781801