GTPases that regulate the myriad of membrane fission events that facilitate the assembly and disassembly of COPII (Sar1), COPI (ARF) and clathrin coats (dynamin) involved in exocytic and endocytic trafficking pathways and mitochrondrial organization remain a major challenge for future investigations to understand membrane architecture of eukaryotic cells. This volume of MIE provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their rapidly expanding list of regulators and effectors. Methodologies focused on biochemical, molecular and advanced imaging techniques provide a wealth of investigational tools for those currently in the field and those entering the field. Many of the methodologies are generally applicable to study of these GTPases in vitro and in vivo to elucidate function in regulation of cell proliferation and signaling in normal tissue and in disease.
*Comprehensive collection of GTPases (ARF, Sar1, Dynamin) GTPases involved in vesicle coat assembly and membrane fission
*Identification and characterization of GTPase GEFs, GAPs and effectors
*General methodologies to study GTPase function in vitro and in vivo
"synopsis" may belong to another edition of this title.
Book Description Academic Press, 2005. Hardcover. Book Condition: New. book. Bookseller Inventory # 0121828093
Book Description Academic Press, 2005. Hardcover. Book Condition: New. 1. Bookseller Inventory # DADAX0121828093
Book Description Academic Press. Hardcover. Book Condition: New. 0121828093 New Condition. Bookseller Inventory # NEW6.1036911
Book Description Elsevier. Book Condition: New. pp. 692. Bookseller Inventory # 7370259
Book Description Book Condition: New. New. US edition. Perfect condition. Ship by express service to USA, Canada, Australia, France, Italy, UK, Germany and Netherland. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-122501
Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB122501
Book Description Book Condition: Brand New. New, US edition. Excellent Customer Service. Bookseller Inventory # ABEUSA-122501
Book Description Book Condition: Brand New. Book Condition: Brand New. Bookseller Inventory # 97801218280971.0
Book Description Book Condition: Brand New. U.S.Edition ,Brand New,Hardcover,Perfect Condition. Printed in English. excellent Quality, and customer satisfaction guaranteed. We Do not Ship APO FPO AND PO BOX. Bookseller Inventory # ABEORGSCB6804
Book Description Db Academic Press. Book Condition: New. This is an Int'l Edition. Please note: We do not ship to PO Boxes, please provide us with your complete delivery address. Bookseller Inventory # DXPCBS1MAR-15305