Neurobiology of Cytokines, Part A (Methods in Neurosciences) (Vol 16)

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9780121852818: Neurobiology of Cytokines, Part A (Methods in Neurosciences) (Vol 16)

Recent data suggest a critical role for cytokines in the regulation of brain and endocrine function under normal physiological conditions. The aim of this volume, and its companion Volume 17, is to provide an overview of the effects of cytokines in the brain and on the endocrine system. Topics covered include: general aspects of cytokines, including the endogenous agonists and antagonists, their receptors, their second messengers, and transport mechanisms for cytokines across the bloodbrain barrier; the anatomical localization of cytokines, cytokine receptors and their respective mRNA in brain and in endocrine tissues; methods for evaluating the "in vivo" and "in vitro" actions of cytokines on hormone secretion.

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