Drug design is intrinsically involved in the discovery of a new drug: it can be incorporated into the identification of a lead compound by intelligent screening; involved when a new molecule for synthesis is created by computer or by intuition, based upon an intelligent understanding of the protein target; or in converting compounds such as peptides and carbohydrates into peptidomimetics or carbohydramimetics, retaining the original role of the compound while operating pharmaceutically. The design element is involved in the application of knowledge of structure-activity relationships to predict activities of designed but yet unsynthesized compounds, and in the synthesis itself. This text updates the first Rhone-Poulenc Rorer Round Table Conference volume on the subject of drug design. It covers topics from the practicalities of synthetic organic chemistry to the potential pitfalls in the mathematics of free-energy calculations.
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Book Description ACADEMIC PRESS INC, 1995. Hardcover. Book Condition: Used; Good. Ships from the UK within 24 hours. Number of pages: 350. With owners inscription. Boards bent. Bookseller Inventory # BBI155659
Book Description Academic Press Inc, 1995. Book Condition: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. , 700grams, ISBN:9780122080708. Bookseller Inventory # 6625510
Book Description Academic Pr. Hardcover. Book Condition: VERY GOOD. Very Good copy, cover and pages show some wear from reading and storage. Binding may have light creases. Lots of life left in these pages. Bookseller Inventory # 2689560190