Aquaporins, Volume 51 (Current Topics in Membranes Series)

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9780123520951: Aquaporins, Volume 51 (Current Topics in Membranes Series)

Aquaporins summarizes the present knowledge in this expanding field of research, starting with the structural analysis of water channel proteins. Subsequent chapters begin with mammalian aquaporins, examining physiology and pathophysiology, analysis of knock-out model animals, and the regulation of aquaporin function. Also covered is the distribution and regulation of aquaporins in plants and the function of water and glycerol channels in microbial systems.

Key Features
* Comprehensive treatment of a topical research field
* Authored by world leaders in the field
* Covers structural biology and physiology
* Covers different experimental and biological systems
* Chapters on plant and microbial systems
* Extensive treatment of mammalian physiology and pathophysiology
* Structural analysis excellently illustrated

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From the Back Cover:

Aquaporin water channels mediate and control the transport of water and small solutes across cellular membranes. The aquaporins belong to an ancient protein family and have been found in all organisms, ranging from bacteria to humans. In this volume, leading researchers discuss recent advances in the analysis of structure, genetics, and physiology of aquaporins. We are now beginning to understand the mechanisms that determine the unique transport specificity of aquaporins. Present knowledge of the role of aquaporins suggests that they will be important targets for drugs treating water imbalances in humans as well as for the genetic engineering of crops for improved performance under limited water availability.
Key Features
* Comprehensive treatment of a topical research field
* Authored by world leaders in the field
* Covers structural biology and physiology
* Covers different experimental and biological systems
* Chapters on plant and microbial systems
* Extensive treatment of mammalian physiology and pathophysiology
* Structural analysis excellently illustrated

About the Author:

Stefan Hohmann, Göeteborg University, Sweden
Peter Agre, Johns Hopkins University School of Medicine, Baltimore, Maryland, U.S.A.
Soren Nielsen, University of Aarhus, Denmark

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