Gaba in Autism and Related Disorders, Volume 71 (International Review of Neurobiology)

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9780123668721: Gaba in Autism and Related Disorders, Volume 71 (International Review of Neurobiology)

Gamma-aminobutyric acid (GABA) was discovered in the brain in 1950 by Eugene Roberts. GABA is now considered one of the most important neurotransmitters and developmental signals. Knowledge on the complexity of GABA function is increasing exponentially. This volume covers basic research on GABA in the developing brain as it may relate to onset of autism and related developmental disorders. The evidence that dysfunction of GABA and related molecules is associated with autism is limited but expanding and seems to converge. Pertinent data are reviewed in this book and new research avenues in the basic and clinical arenas are described. The topics are of imminent interest to basic and clinical researchers as well as interested clinicians.

* Discusses the neuropathology of the GABA system in autism
* Presents new findings on common genetic mechanisms in Rett syndrome, Angelman syndrome, and autism
* Includes information on the shared genetic risk factors between autism and major mental disorders
* Foreword by Eugene Roberts

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Presents the latest findings on the effects of GABA on the developing brain, including its link to autism and related developmental disorders.

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Editor-Dirk Marcel Dhossche
Published by Academic Press (2005)
ISBN 10: 0123668727 ISBN 13: 9780123668721
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