Genetic Instabilities and Neurological Diseases, Second Edition, Second Edition

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9780123694621: Genetic Instabilities and Neurological Diseases, Second Edition, Second Edition

This book describes everything about DNA repeat instability and neurological disorders, covering molecular mechanisms of repeat expansion, pathogenic mechanisms, clinical phenotype, parental gender effects, genotype-phenotype correlation, and diagnostic applications of the molecular data. This updated edition provides excellent updates of these repeat expansion mutations, including the addition of many new chapters, and old chapters rewritten as extensions of the previous edition. This edition also features a CD-ROM containing all of the figures from the book. This book is an invaluable reference source for neuroscientists, geneticists, neurologists, molecular biologists, genetic counsellors and students.

* Includes a CD-ROM with all of the figures
* Contributions by most of the principal research teams in the area, edited by world-renowned leaders
* Lays the background for future investigations on related diseases

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An updated review of the clinical, genetic, molecular, biological and biophysical investigations of neurological diseases.

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