The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation - Softcover

Sherbet, G. V.

9780123909428: The Genetics of Cancer: Genes Associated with Cancer Invasion, Metastasis and Cell Proliferation

Softcover

ISBN 10: 0123909422 ISBN 13: 9780123909428

Publisher: Academic Press, 2011

Written by internationally recognized experts, The Genetics of Cancer provides up-to-date information and insight into the genetic basis of cancer and the mechanisms involved in cancer invasion and its secondary spread. This volume presents the deregulation of the cell cycle in tumor development and integrates the function of tumor suppressor genes, oncogenes, and metastasis-associated genes in the pathogenesis and progression of cancer. The Genetics of Cancer will be useful to all graduate students, clinicians, and researchers working in the fields of cancer biology, genetics, and molecular biology.

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From the Back Cover:

An understanding of the genetic basis of cancer and the mechanisms governing cancer invasion and its secondary spread are fundamental to our ability to design appropriate treatments.
This book, written by internationally recognised experts in cancer biology, provides insights into the deregulation of the cell cycle in tumour development and integrates the function of tumour suppressor genes, oncogenes and metastasis-associated genes in the pathogenesis and progression of cancer.
This volume presents an up to date and comprehensive coverage of current research in the field.
The contents include:
* Clonal evolution of the metastasis phenotype
* Cell Cycle regulation
* Apoptosis in tumour growth and metastasis
* Angiogenesis in cancer
* Cell surface glycoproteins and their receptors
* Proteinases and their inhibitors in cancer invasion
* Oncogenes and cancer metastasis
* Developmental genes
* Tumour suppressor genes
* Metastasis suppressor genes
* Dominant metastasis-associated genes
This book will be of interest to all graduates, clinicians and researchers working in the fields of cancer biology, genetics and molecular biology.

About the Author:

Dr. G.V. Sherbet is a Fellow of the Institute of Biology and a Fellow of the Royal College of Pathologists. He was a member of the scientific staff at the Chester Beatty Research Institute and University College Medical School of London, and since 1977, he has been at the Cancer Research Unit in the Medical School of University of Newcastle upon Tyne. He has held several prestigious fellowships, such as the Beit Memorial and the Williams and Cancer Research Campaign Fellowships. Dr. Sherbet is currently the Deputy Director of the Cancer Research Unit and Reader in Experimental Oncology.

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