Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care

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9780123973368: Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care

Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development.

With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development.

  • Provides case studies in applications of pharmacodynamic and predictive markers in drug development in oncology, autoimmunity, respiratory diseases and infectious diseases
  • Shows how to identify potential new therapeutic targets in different diseases and provides examples of potential new disease indications for life cycle management of drugs
  • Authored by leading international experts from industry and academia

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About the Author:

PhD, MedImmune, Gaithersburg, MD

PhD, MedImmune, Gaithersburg, MD

PhD, MedImmune, Gaithersburg, MD

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"After a good overview of the knowledge in this area, excellent chapters describe how genomics is applicable to some common diseases. The book covers important methodology required to advance personalized medicine and clearly outlines challenges to moving this field forward." Rating: 3 Stars--Doody.com, April 25, 2014

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Yihong Yao (editor), Bahija Jallal (editor), Koustubh Ranade (editor)
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Book Description Book Condition: New. Publisher/Verlag: Academic Press | Advancing Personalized Health Care | Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development.With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development.Provides case studies in applications of pharmacodynamic and predictive markers in drug development in oncology, autoimmunity, respiratory diseases and infectious diseasesShows how to identify potential new therapeutic targets in different diseases and provides examples of potential new disease indications for life cycle management of drugsAuthored by leading international experts from industry and academia | PrefaceAcknowledgements1. Application of TS in clinical development2. Personalized Healthcare (PHC) in cancer3. PHC in autoimmune diseases4. PHC in respiratory diseases5. miRNA as potential Diagnostic Marker6. Toxicogenomics7. Translating Biomarker Discovery into Companion Diagnostics Through Validation and Regulatory Consideration | Format: Hardback | Language/Sprache: english | 590 gr | 240x185x16 mm | 208 pp. Bookseller Inventory # K9780123973368

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Book Description Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Book Condition: New. Language: English . Brand New Book. Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development. Bookseller Inventory # AA59780123973368

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Book Description Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Book Condition: New. Language: English . Brand New Book. Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development. Bookseller Inventory # AA59780123973368

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Book Description Elsevier Science Publishing Co Inc, United States, 2013. Hardback. Book Condition: New. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Genomic Biomarkers for Pharmaceutical Development: Advancing Personalized Health Care provides an in-depth review of the state of translational science across all stages of pharmaceutical development with a special focus on personalized health care. This book provides a complete picture of biomarker development and validation in a pharmaceutical setting while addressing the inherent challenges of targeting the appropriate indications, biomarker robustness, regulatory hurdles, commercialization and much more. It features case studies devoted to the applications of pharmacogenomics, toxicogenomics, and other genetic technologies as they support drug discovery and development. With chapters written by international authorities in industry and academia, this work is a truly unique presentation of the thoughts and approaches that lead to the development of personalized medicine. Intended for all those involved in clinical translational research, this book is the ideal resource for scientists searching for the applications, strategies and successful approaches of translational science in pharmaceutical development. Bookseller Inventory # BZE9780123973368

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