Cocaine Abuse: Behavior, Pharmacology, and Clinical Applications

 
9780123992307: Cocaine Abuse: Behavior, Pharmacology, and Clinical Applications

Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. Cocaine abuse results from a complex interplay of behavioral, pharmacological, and neurobiological determinants. While a complete understanding of cocaine abuse is currently beyond us, significant progress has been made in preclinical research on fundamental determinants of this disorder. These advances are critically reviewed in the first section of this volume. Important advances also have been made in characterizing the clinical pharmacology of cocaine, and those advances have been extended to understanding individual vulnerability to cocaine abuse, development of effective treatments, and discussions of policy. Those advances are critically reviewed in the third section of this volume. Contributors to the book were selected because of their status as internationally recognized leaders in their respective areas of scientific expertise. Moreover, each is a proponent of the importance of a rigorous, interdisciplinary scientific approach to effectively addressing the problem of cocaine abuse. As such, this volume offers a coherent, empirically-based conceptual framework for addressing cocaine abuse that has continuity from the basic research laboratory through the clinical and policy arenas. Each of the specific chapters is sufficiently detailed, in-depth and current to be valuable to informed readers with specific interests while also offering a comprehensive overview for those who might be less informed or have broader interests in cocaine abuse. This blend of critical review within each chapter with an explicitly conceptual continuity that spans all of the chapters makes this volume a unique contribution to cocaine abuse in particular and substance abuse in general.

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From the Back Cover:

Cocaine abuse remains a major public health problem and contributes to many of our most disturbing social problems, including the spread of infectious disease, crime, violence, and neonatal drug exposure. provides a comprehensive review of the complex interplay of behavioral, pharmacological, and neurobiological factors and explains the significant progress in preclinical research on fundamental determinants of this disorder.
Important advances also have been made in characterizing the clinical pharmacology of cocaine, and those advances have been extended to understanding individual vulnerability to cocaine abuse, developing effective treatments, and discussing policy. Cocaine Abuse offers a coherent, empirically based conceptual framework for addressing cocaine abuse that has continuity from the basic research laboratory through the clinical and policy arenas.
Each of the specific chapters is sufficiently detailed, in-depth and current to be valuable to informed readers with either specific or broad interests in cocaine abuse. This blend of critical review within each chapter with an explicitly conceptual continuity that spans all of the chapters makes this volume a unique contribution to cocaine abuse in particular and substance abuse research in general.

About the Author:

Dr. Higgins has received numerous scientific awards, is President-elect of the Division of Psychopharmacology and Substance Use of the American Psychological Association, is Principal and Co-Investigator on numerous federal research grants, and publishes extensively on cocaine abuse in the scientific literature. He earned his Ph.D. from the University of Kansas in 1983. He was a post-doctoral fellow at the Johns Hopkins University School of Medicine from 1983-1984. From 1985-1986, Dr. Higgins was a staff fellow at the Addiction Research Center of the National Institute of Drug Abuse in Baltimore, Maryland. In 1986, he joined the faculty of the University of Vermont where he is now Professor of Psychiatry and Psychology. His research is a blend of laboratory and treatment-outcome research, primarily focused on developing effective treatments for cocaine abuse.

Dr. Jonathan L. Katz received his Ph.D. in Psychology at the University of Maryland in 1973. He received fellowships from the National Institute of Mental Health and the National Institute on Drug Abuse. He obtained postgraduate training in the Laboratory of Psychobiology at the Harvard Medical School. Following that training he was on the research faculty of the Department of Pharmacology at the University of Michigan Medical School from 1980 to 1982. The next year he took a position in the Intramural Research Program of the National Institute on Drug Abuse, where he serves as Chief of the Psychobiology Section. In addition, Dr. Katz holds the position of Adjunct Associate Professor in the Department of Pharmacology and Experimental Therapeutics at the University of Maryland School of Medicine. Dr. Katz engages in public and professional service through several professional societies and government agencies, and has published extensively in the scientific literature.

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Stephen T. Higgins
Published by Academic Press
ISBN 10: 0123992303 ISBN 13: 9780123992307
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