Channels, Carriers, and Pumps, Second Edition: An Introduction to Membrane Transport

0 avg rating
( 0 ratings by Goodreads )
 
9780124165793: Channels, Carriers, and Pumps, Second Edition: An Introduction to Membrane Transport

An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered.

  • Provides an introduction to the properties of transport proteins: channels, carriers, and pumps
  • Presents up-to-date information on the structure of transport proteins and on their function and regulation
  • Includes introductions to transport kinetics and to the cloning of genes that code transport proteins
  • Furnishes a link between the experimental basis of the subject and theoretical model building

"synopsis" may belong to another edition of this title.

About the Author:

Wilfred Stein is the author of three previous books on membrane transport, the first appearing almost fifty years ago. He has edited numerous books and written some 180 papers on various aspects of membrane transport and especially transport kinetics. These papers, especially those written together with his colleague William Lieb, defined many of the concepts used today in discussing movement across cell membranes. More recently he has turned to the study of the kinetics of drugs used in cancer therapy and in the treatment of malaria. He has taught biochemistry, biophysics and physiology at the University of Manchester and the Hebrew University of Jerusalem and also at the Weizmann Institute in Israel. He is currently Emeritus Professor of Biophysics at the Hebrew University. He is married to a librarian and has four children and nine grandchildren.

Thomas Litman works as a senior research scientist at LEO Pharma, where he is responsible for implementing bioinformatics in translational research. He has taught biophysics and transport physiology at the University of Copenhagen since 1994 and is the author of some 70 papers, most of which focus on multidrug resistance and functional characterization of drug transporters, such as P-glycoprotein. In particular the papers on transport kinetics of anticancer drugs, written together with his mentor, Professor Wilfred Stein, have been recognized as exemplary in the field. He completed his post-doctoral work at The National Cancer Institute, NIH 1997-9, where he played a key role in the identification and characterization of a new transporter, ABCG2 (MXR), involved in multidrug resistance. In 2002 he was appointed as Weimann associate research professor, and 2003-6 he was responsible for the master’s program in medical bioinformatics at the Bioinformatics Centre, University of Copenhagen. His interests range from basic and translational research to information technology and applied bioinformatics, including confocal microscopy, microarray analysis, noncoding RNA, proteomics, next-generation sequencing, and molecular modeling.

Review:

"...an excellent resource on the current understanding of channels, carriers, and pumps as well as transport processes and their important roles in health and disease. Score: 91 = 4 Stars"--Doody's, Channels, Carriers, and Pumps, Second Edition

Praise for the previous edition: It has become the "Bible" for my lab. ~Tony Carruthers, Dean, Graduate School of Biomedical Sciences, UMass Medical School

The strength of this book is the way in which rigorous yet lucid expositions of the theoretical basis of various types of transport are integrated with illuminating discussions of experimental results. [This book] will continue to be rewarding reading when many symposium reports have become outdated, and it is warmly welcomed and recommended. ~D.K. Apps, FEBS LETTERS, August 1991

With so much diversity in biology it is exhilarating to read Stein’s attempt at synthesis. More of this is needed . . . Stein’s book should earn a place of its own, for it does something that few others attempt: it puts channels, carriers, and pumps under one roof . . . the book’s greatest value: its potential for catalytic action on sometimes disparate fields. ~Louis J. DeFelice, California Institute of Technology, CELL, August 1991

"About this title" may belong to another edition of this title.

Buy New View Book
List Price: US$ 130.00
US$ 81.42

Convert Currency

Shipping: FREE
From United Kingdom to U.S.A.

Destination, Rates & Speeds

Add to Basket

Top Search Results from the AbeBooks Marketplace

1.

Wilfred Stein, Thomas Litman
Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Hardcover Quantity Available: 1
Seller
The Book Depository
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 2nd Revised edition. 241 x 165 mm. Language: English . Brand New Book. An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Bookseller Inventory # AA59780124165793

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 81.42
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

2.

Wilfred Stein,Thomas Litman
Published by Elsevier Science Publishing Co Inc 2014-12-01 (2014)
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Hardcover Quantity Available: 5
Seller
Chiron Media
(Wallingford, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc 2014-12-01, 2014. Hardcover. Book Condition: New. Bookseller Inventory # NU-ELS-00005443

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 78.15
Convert Currency

Add to Basket

Shipping: US$ 3.83
From United Kingdom to U.S.A.
Destination, Rates & Speeds

3.

Wilfred Stein, Thomas Litman
Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Hardcover Quantity Available: 1
Seller
The Book Depository US
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 2nd Revised edition. 241 x 165 mm. Language: English . Brand New Book. An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Bookseller Inventory # AA59780124165793

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 82.77
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

4.

Stein, Wilfred
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
Bookshub
(Karol Bagh, India)
Rating
[?]

Book Description Book Condition: New. New. US edition. Perfect condition. Ship by express service to USA, Canada, Australia, France, Italy, UK, Germany and Netherland. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-16067

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 95.36
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds

5.

Wilfred D. Stein
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
Bookshub
(Karol Bagh, India)
Rating
[?]

Book Description Book Condition: New. New. US edition. Perfect condition. Ship by express service to USA, Canada, Australia, France, Italy, UK, Germany and Netherland. Customer satisfaction our priority. Bookseller Inventory # ABE-FEB-16068

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 95.36
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds

6.

Stein, Wilfred
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
EBOOKSTORE2010
(New Delhi, ND, India)
Rating
[?]

Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB16067

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 95.41
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds

7.

Wilfred D. Stein
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
EBOOKSTORE2010
(New Delhi, ND, India)
Rating
[?]

Book Description Book Condition: Brand New. New. US edition. Customer Satisfaction guaranteed!!. Bookseller Inventory # SHUB16068

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 95.41
Convert Currency

Add to Basket

Shipping: FREE
From India to U.S.A.
Destination, Rates & Speeds

8.

Stein, Wilfred
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
Basi6 International
(Irving, TX, U.S.A.)
Rating
[?]

Book Description Book Condition: Brand New. New, US edition. Excellent Customer Service. Bookseller Inventory # ABEUSA-16067

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 99.26
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

9.

Wilfred D. Stein
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
Basi6 International
(Irving, TX, U.S.A.)
Rating
[?]

Book Description Book Condition: Brand New. New, US edition. Excellent Customer Service. Bookseller Inventory # ABEUSA-16068

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 99.26
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

10.

Wilfred D. Stein
ISBN 10: 0124165796 ISBN 13: 9780124165793
New Quantity Available: 1
Seller
Rem Distributors
(NORWALK, CT, U.S.A.)
Rating
[?]

Book Description Book Condition: New. Dust Jacket Condition: New. Shipped promptly and delivered within 3 to 5 working days. For PO BOX, APO, FPO and Puerto Rico addresses delivery done in 20 to 25 working days. Serving customers since 2006. Thousand of satisfied customers!. Bookseller Inventory # REG_9780124165793_Elsev1012_74

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 99.65
Convert Currency

Add to Basket

Shipping: US$ 3.95
Within U.S.A.
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book