Crystallography Made Crystal Clear, Second Edition: A Guide for Users of Macromolecular Models (Complementary Science)

4.5 avg rating
( 2 ratings by Goodreads )
 
9780125870726: Crystallography Made Crystal Clear, Second Edition: A Guide for Users of Macromolecular Models (Complementary Science)

Macromolecules are the proteins and nucleic acids upon which life depends. Understanding the action of biological macromolecules (giant molecules) requires detailed knowledge of their structures. Most of the more than ten thousand known structures of protein and nucleic acids were obtained by x-ray crystallography, the standard mechanism for determining protein structure. Essentially, proteins are frozen into rigid crystals, which can be stacked up in a repeating pattern--like supermarket displays. The structure of each individual crystal can be determined by the way x-rays are bent when they pass through the composite crystal. Protein structure is essential when investigating protein interactions and planning drug development.
Crystallography Made Crystal Clear, Second Edition explains how scientists discover the structures of the macromolecules. Scientists do not see these molecules directly. Instead, they build models as a means of interpreting data from x-ray diffraction by crystals, or by irradiation by other forms of energy. Users of these models need to know how they are obtained in order to know what they are seeing when they study a model of a macromolecule. They also need to know how to judge whether conclusions they draw from the molecular models are really supported by the models. This book uses visual and geometric models to help readers understand the mathematics that forms the basis of x-ray crystallography.
The field of protein crystallography is growing every day and has been instrumental in discovering the molecular principles of biology and in discovering new drugs, such as the recent protease inhibitors for AIDS. The field includes the largest percentage of Nobel prizes than any other scientific discipline. Every major university and drug company has a protein crystallography laboratory and this book is an invaluable aid to those wishing to practice protein crystallography
or just learn more about how it is actually done.

Key Features
* Provides clear, understandable descriptions of principles of X-ray crystallography
* Leads reader through unintimidating and thorough explanations of the underlying mathematics
* Provides abundant illustrations, including diagrams, charts, photographs, and color stereo
* images
* Explains how to read crystallography papers in research journals
* Includes brief descriptions of other diffraction methods (neutron, electron, Laue) and the kinds
* of structural information they can provide
* Introduces other methods of macromolecular structure determination (NMR spectroscopy and
* homology modeling), and provides guidance in judging the quality of these models

"synopsis" may belong to another edition of this title.

Book Description:

Expanded and updated edition uses four-color art and concise language to explain the basis of X-ray crystallography

From the Back Cover:

Gale Rhodes makes crystallography accessible to readers who have no prior knowledge of the field, or its mathematical basis. The second edition of Crystallography Made Crystal Clear has been fully updated and expanded to make it the most comprehensive and concise reference for beginning crystallographers. The book also introduces essential World Wide Web tools for users of models, including beginning-level tutorials in molecular modeling on personal computers. The CMCC Home Page (www.usm.maine.edu/~rhodes/CMCC) provides access to all tools and links to all resources discussed in this book. Most significantly, the final chapter introduces the reader to macromolecular modeling on personal computers-featuring SwissPdbViewer, a free, powerful modeling program now available for PC, Power Macintosh, and Unix computers.
Key Features
* Provides clear, understandable descriptions of principles of X-ray crystallography
* Leads reader through unintimidating and thorough explanations of the underlying mathematics
* Provides abundant illustrations, including diagrams, charts, photographs, and color stereo
* images
* Explains how to read crystallography papers in research journals
* Includes brief descriptions of other diffraction methods (neutron, electron, Laue) and the kinds
* of structural information they can provide
* Introduces other methods of macromolecular structure determination (NMR spectroscopy and
* homology modeling), and provides guidance in judging the quality of these models

"About this title" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

1.

Rhodes, Gale
Published by Academic Press (1999)
ISBN 10: 0125870728 ISBN 13: 9780125870726
New Paperback Quantity Available: 2
Seller
Murray Media
(North Miami Beach, FL, U.S.A.)
Rating
[?]

Book Description Academic Press, 1999. Paperback. Book Condition: New. Bookseller Inventory # P110125870728

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 59.58
Convert Currency

Add to Basket

Shipping: US$ 2.99
Within U.S.A.
Destination, Rates & Speeds

2.

Gale Rhodes
Published by Academic Press (1999)
ISBN 10: 0125870728 ISBN 13: 9780125870726
New Paperback Quantity Available: 1
Seller
Ergodebooks
(RICHMOND, TX, U.S.A.)
Rating
[?]

Book Description Academic Press, 1999. Paperback. Book Condition: New. 2. Bookseller Inventory # DADAX0125870728

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 87.74
Convert Currency

Add to Basket

Shipping: US$ 3.99
Within U.S.A.
Destination, Rates & Speeds