The Compendium is a detailed compilation of chiral auxiliaries which are used in the field of organic chemistry to direct "asymmetric synthesis". A molecule is called chiral because it can have two "enantiomers" -- like left and right-handed molecules. An enantiomer is either of two molecules of the same chemical composition that are mirror images of each other but not identical. A "chiral auxiliary" is an aid / auxiliary used to specifically produce either the left or right enantiomer of the chosen molecule, as desired. In this comprehesive reference source, industrial chemists can make informed selections of an auxiliary for a specific application. It is fully cross-referenced to enable the comparative selection of auxiliaries. The work includes over 13,000 auxiliary reaction applications with complete reaction details of the synthetic routes, reagents, and primary literature references.
* This remarkable major reference work is the first such compilation and represents the only total source for the diverse applications of auxiliaries
* Thoroughly cross-referenced to enable comparative
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A comprehensive and detailed compilation of chiral auxiliaries--this unique source of information will prove of vital importance to the pharmaceutical and fine chemical industriesAbout the Author:
Greg Roos obtained his formal education, comprising of a BSc (1971), BSc Honours (1972), and PhD in Organic Synthesis (1976), at the University of Cape Town. A postdoctoral fellowship (1978) with Richard Cookson at the University of Southampton was followed by a few years of pharmaceutical industrial experience. His full-time academic career began at the University of Natal, Pietermaritzburg (1981-1994), and continued at Murdoch University, Perth, Australia (1994-1997). This was followed by an extended period in the Middle East, including Sultan Qaboos University, Oman (1998-2004) and The Petroleum Institute, Abu Dhabi (2004-2008). He has successfully taught across various cultures and has received awards for his teaching contributions and innovations. Currently, as an adjunct Professor at Murdoch University (since 2009), he now shares his time between Perth and Dubai.
His research interests have focused on the development of synthetic methodology, with particular interest in asymmetric processes. This led to numerous publications and conference contributions in the areas of the Baylis-Hillman reaction, imidazolidinone chiral auxiliaries, and dirhodium catalyst development and applications. This period also included a number of collaborative research visits with Tony McKervey (University College Cork & Queen's University, Belfast), C. K. Sha (Shin Hua University, Taiwan), Mike Doyle (Trinity University, San Antonio), and Ron Warrener (CQU Rockhampton, Queensland). In 2001, he received the Merck Gold Medal for research from the South African Chemical Institute.
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