Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma.
* Presents the recent progress made in the research on the blood-brain and spinal cord barrier
* Contains numerous illustrations of light and electron micrographs
* Includes Foreword written by two eminent researchers in the field, Milton Brightman and Jorge Cervos-Navarro
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Discusses the role of the blood-brain and blood-spinal barriers in human health and disease.About the Author:
Hari Shanker Sharma, Doctor of Medical Sciences, Uppsala University, has been actively engaged in CNS injury and repair research for several decades and is one of the world leaders in the field of blood-brain barrier research. Dr. Sharma s work is focused on the role of the blood-brain barrier in CNS injuries and repair using pharmacological and morphological approaches. Dr. Sharma has edited 4 books and authored over 100 refereed research papers in numerous neuroscience journals. Dr. Sharma s most recent research suggests that the blood-brain and spinal cord barrier appears to be the gateway of various neurological diseases.
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