The Complement FactsBook

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9780127333601: The Complement FactsBook

The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies.

Key Features
* Includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies
* Presents detailed structural information including cDNA and gene structure for all proteins
* Introduces complement function, simply described for each function
* Data is as up-to-date as possible, including unpublished work from many contributors
* Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families
* Each chapter has been written by an expert in the field
* Data is as up-to-date as possible, including unpublished work from many contributors
Entries provide information on:
* Alternative nomenclature
* Physiochemical properties
* Structure and function
* Tissue distribution and regulation expression
* Protein sequence/modules
* Chromosomal location
* Genomic structure
* Database accession numbers
* Deficiency and polymorphic variants
* Key references

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From the Back Cover:

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and structure? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBooks series has established itself as the best source of easily-accessible and accurate facts about protein groups. Described as 'A growing series of excellent manuals' by Molecular Medicine Today, and 'Essential works of reference' by Trends in Biochemical Sciences, the FactsBooks have become the most popular comprehensive data resources available. Using an easy-to-follow format, the Factsbooks will keep you up-to-date with the latest advances in structure, amino acid sequences, physicochemical properties, and biological activity. Meticulously researched and compiled by experts in the field, keeping abreast of developments has never been so easy!
The Complement FactsBook contains entries on all the components of the Complement system, including C1q and Collectins, C3 Family Proteins, Serine Proteases, Regulators of Complement Activation, Cell Surface Receptors and Terminal Pathway proteins.
Entries provide information on:
* alternative nomenclature
* physiochemical properties
* structure & function
* tissue distribution & regulation of expression
* protein sequence/modules
* chromosomal location
* cDNA sequence and intron-exon boundaries
* genomic structure
* database accession numbers
* deficiency & polymorphic variants
* key references

About the Author:

Dr. Bernard Morely is a senior lecturer in the Division of Medicine of the Imperial College School of Medicine. He studied biochemistry at Liverpool University before training for his doctorate at Oxford in the late Dr. Rodney Porter's unit. Here he worked on cloning Factor B with Duncan Campbell. After several years of work in the USA and the UK on globin expression and its regulation, he returned to complement research at the Hammersmith Hospital. His present research interests are in the genetics of SLE and the regulation of gene expression.

Professor Mark Walport is a professor of medicine and the head of the Division of Medicine at Imperial College School of Medicine. He was previously Director of Research and Development fot the Hammersmith Hospitals Trusts. He trained at Cambridge University and the Middlesex Hospital Medical School. After junior clinical training posts, he undertook a Ph.D. in Cambridge supervised by Professor Peter Lachmann. From there he moved in 1985 to the Royal Postgraduate Medical School at Hammersmith Hospital. His research interests are in the genetics of the complement system and in the inherited mechanisms of susceptibility to autoimmune rheumatic diseases.

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Book Description U.K / Academic Press, 2000. Soft cover. Book Condition: New. No Jacket. The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. Part of the 'Fact Book' series of books. A 1st edition paperback, in new condition. (228 pages). Bookseller Inventory # 2731

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Book Description Elsevier Science Publishing Co Inc, United States, 2000. Paperback. Book Condition: New. 228 x 150 mm. Language: English . Brand New Book. The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. Key Features * Includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies * Presents detailed structural information including cDNA and gene structure for all proteins * Introduces complement function, simply described for each function * Data is as up-to-date as possible, including unpublished work from many contributors * Incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families * Each chapter has been written by an expert in the field * Data is as up-to-date as possible, including unpublished work from many contributors Entries provide information on: * Alternative nomenclature * Physiochemical properties * Structure and function * Tissue distribution and regulation expression * Protein sequence/modules * Chromosomal location * Genomic structure * Database accession numbers * Deficiency and polymorphic variants * Key references. Bookseller Inventory # AA59780127333601

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Book Description Elsevier Science Publishing Co Inc, United States, 2000. Paperback. Book Condition: New. 228 x 150 mm. Language: English . Brand New Book. The Complement FactsBook contains entries on all components of the Complement System, including C1q and Lectins, C3 Family, Serine Proteases, Serum Regulators of Complement Activation, Cell Surface Proteins, and Terminal Pathway Proteins. Domain Structure diagrams are incorporated to clearly illustrate the relationships between all the complement proteins, both within families and between families. The FactsBook also includes the cDNA sequences, marked with intron/exon boundaries, which will facilitate genetic studies. It includes the cDNA sequences, marked with intron/exon boundaries, facilitating genetic studies. It presents detailed structural information including cDNA and gene structure for all proteins. It introduces complement function, simply described for each function. The data is as up-to-date as possible, including unpublished work from many contributors. It incorporates domain structures diagrams, which beautifully illustrate the relationship between all the complement proteins, both within, and between, families. Each chapter has been written by an expert in the field. The entries provide information on: Alternative nomenclature; Physiochemical properties; Structure and function; Tissue distribution and regulation expression; Protein sequence/modules; Chromosomal location; Genomic structure; Database accession numbers; Deficiency and polymorphic variants; and key references. Bookseller Inventory # AA59780127333601

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