Molecular Targets in Protein Misfolding and Neurodegenerative Disease

0 avg rating
( 0 ratings by GoodReads )
 
9780128001868: Molecular Targets in Protein Misfolding and Neurodegenerative Disease

Aimed at "drug discoverers" - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc.

  • Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases
  • Provides a "drug discovery” application oriented perspective, evaluating targets and candidates for their overall therapeutic potential
  • Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development
  • Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area
  • Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets

"synopsis" may belong to another edition of this title.

About the Author:

Dr. Pierfausto Seneci is Associate Professor in the Department of Organic and Industrial Chemistry at the University of Milan. He is currently affiliated with the University of Milan Centre for Interdisciplinary Biomolecular Studies and Industrial Applications (CISI) Centre of Excellence, and is responsible for the Combinatorial Chemistry/High Throughput MedChem Laboratory. He has over 20 years of medicinal chemistry experience working in industry, and held business development positions with GSK, Sanofi, and start-up pharmaceutical companies including Sirenade and NiKem working in drug discovery, neurodegeneration, oncology, and antibacterials. He is author of approximately 80 papers on the topic and several book chapters, including the book "Solid-Phase Synthesis and Combinatorial Technologies” with Wiley-Interscience in 2000.

"About this title" may belong to another edition of this title.

Top Search Results from the AbeBooks Marketplace

1.

Seneci, Pierfausto
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Quantity Available: 3
Seller
GreatBookPrices
(Columbia, MD, U.S.A.)
Rating
[?]

Book Description Book Condition: New. Bookseller Inventory # 21967699-n

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 67.01
Convert Currency

Add to Basket

Shipping: US$ 2.64
Within U.S.A.
Destination, Rates & Speeds

2.

Seneci, Pierfausto
Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover Quantity Available: 1
Seller
The Book Depository US
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 246 x 166 mm. Language: English . Brand New Book. Aimed at drug discoverers - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. Bookseller Inventory # AAU9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 81.03
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

3.

Seneci, Pierfausto
Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover Quantity Available: 1
Seller
The Book Depository
(London, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 246 x 166 mm. Language: English . Brand New Book. Aimed at drug discoverers - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. * Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases* Provides a drug discovery application oriented perspective, evaluating targets and candidates for their overall therapeutic potential* Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development* Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area* Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets. Bookseller Inventory # AAU9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 83.16
Convert Currency

Add to Basket

Shipping: FREE
From United Kingdom to U.S.A.
Destination, Rates & Speeds

4.

Seneci, Pierfausto
Published by Elsevier Science Publishing Co Inc 2014-10-09, San Diego (2014)
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover Quantity Available: 1
Seller
Blackwell's
(Oxford, OX, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc 2014-10-09, San Diego, 2014. hardback. Book Condition: New. Bookseller Inventory # 9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 82.98
Convert Currency

Add to Basket

Shipping: US$ 5.52
From United Kingdom to U.S.A.
Destination, Rates & Speeds

5.

Seneci, Pierfausto
Published by Elsevier Science Publishing Co Inc
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover Quantity Available: 3
Seller
THE SAINT BOOKSTORE
(Southport, United Kingdom)
Rating
[?]

Book Description Elsevier Science Publishing Co Inc. Hardback. Book Condition: new. BRAND NEW, Molecular Targets in Protein Misfolding and Neurodegenerative Disease: Focus on Tau, Alzheimer's Disease, and Other Tauopathies, Pierfausto Seneci, Aimed at "drug discoverers" - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc. * Written to provide a comprehensive coverage of disease-modifying mechanisms and compounds against neurodegenerative diseases* Provides a "drug discovery application oriented perspective, evaluating targets and candidates for their overall therapeutic potential* Provides discipline-specific chapters (medicinal chemistry, target validation, preclinical and clinical development* Provides an overview on a number of molecular mechanisms (e.g. phosphorylation, chaperon refolding, ubiquitination, autophagy, microtubule transportation, protease cleavage, etc.) with relevance for any disease area* Contains a more thorough description of the therapeutic relevance of ~10 specific molecular targets. Bookseller Inventory # B9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 82.23
Convert Currency

Add to Basket

Shipping: US$ 7.28
From United Kingdom to U.S.A.
Destination, Rates & Speeds

6.

Seneci, Pierfausto
Published by Academic Press (2014)
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover First Edition Quantity Available: 3
Rating
[?]

Book Description Academic Press, 2014. Book Condition: New. Num Pages: 314 pages, colour illustrations, figures. BIC Classification: MJN; MMG. Category: (P) Professional & Vocational. Dimension: 239 x 152 x 18. Weight in Grams: 648. . 2014. 1st Edition. Hardcover. . . . . . Bookseller Inventory # V9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 91.34
Convert Currency

Add to Basket

Shipping: FREE
From Ireland to U.S.A.
Destination, Rates & Speeds

7.

Seneci, Pierfausto
Published by Academic Press (2014)
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Quantity Available: 3
Seller
Books2Anywhere
(Fairford, GLOS, United Kingdom)
Rating
[?]

Book Description Academic Press, 2014. HRD. Book Condition: New. New Book. Shipped from UK in 4 to 14 days. Established seller since 2000. Bookseller Inventory # BB-9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 82.37
Convert Currency

Add to Basket

Shipping: US$ 11.03
From United Kingdom to U.S.A.
Destination, Rates & Speeds

8.

Seneci, Pierfausto
Published by Academic Press
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover Quantity Available: 3
Seller
Kennys Bookstore
(Olney, MD, U.S.A.)
Rating
[?]

Book Description Academic Press. Book Condition: New. Num Pages: 314 pages, colour illustrations, figures. BIC Classification: MJN; MMG. Category: (P) Professional & Vocational. Dimension: 239 x 152 x 18. Weight in Grams: 648. . 2014. 1st Edition. Hardcover. . . . . Books ship from the US and Ireland. Bookseller Inventory # V9780128001868

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 93.80
Convert Currency

Add to Basket

Shipping: FREE
Within U.S.A.
Destination, Rates & Speeds

9.

Seneci, Pierfausto
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover First Edition Quantity Available: 3
Seller
Ria Christie Collections
(Uxbridge, United Kingdom)
Rating
[?]

Book Description Hardback. Book Condition: New. Not Signed; Aimed at drug discoverers - i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular - the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline. book. Bookseller Inventory # ria9780128001868_rkm

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 91.35
Convert Currency

Add to Basket

Shipping: US$ 4.09
From United Kingdom to U.S.A.
Destination, Rates & Speeds

10.

Seneci, Pierfausto
Published by Academic Pr (2014)
ISBN 10: 0128001860 ISBN 13: 9780128001868
New Hardcover Quantity Available: 1
Seller
Revaluation Books
(Exeter, United Kingdom)
Rating
[?]

Book Description Academic Pr, 2014. Hardcover. Book Condition: Brand New. har/psc edition. 295 pages. 9.00x6.25x0.75 inches. In Stock. Bookseller Inventory # __0128001860

More Information About This Seller | Ask Bookseller a Question

Buy New
US$ 93.26
Convert Currency

Add to Basket

Shipping: US$ 7.36
From United Kingdom to U.S.A.
Destination, Rates & Speeds

There are more copies of this book

View all search results for this book