Translating Regenerative Medicine to the Clinic (Advances in Translational Medicine)

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9780128005484: Translating Regenerative Medicine to the Clinic (Advances in Translational Medicine)

Translating Regenerative Medicine to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. It features the uses of regenerative medicine for different disease treatment areas organized by organ and tissue areas, including cardiovascular disease, muscle regeneration and regeneration of the bone and skin. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field.   The book promotes cross-disciplinary communication between the sub-specialities of medicine, but in common with the rest of the books in Translational Medicine, remains unified in theme by emphasizing recent innovations, critical barriers to progress and the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the Series

Volume I: Translating Gene Therapy to the Clinic. Reviews the latest research in gene transfer, genome engineering and clinical trials, as gene-based therapeutic techniques move from the lab to the clinic.

Volume II: Translating Regenerative Medicine to the Clinic. Describes regenerative medicine and stem cell biology as both transition from applied biology to clinical translation.

Volume III: Translating MicroRNAs to the Clinic. Outlines the new uses of microRNA for clinical application across the full spectrum of targeting, biomarkers and active treatment.

Volume IV: Translating Biomarkers to the Clinic. Comprehensively reviews modern research in translational biomarkers, for therapeutic evaluation of specific diseases.

Volume V: Translating Epigenetics to the Clinic. Reviews the myriad of translational possibilities in biological epigenetics, from basic science discoveries to current clinical trials of new pharmacoepigenetic therapies.

  • Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic
  • Extensive pedagogical updates aiming to improve the education of translational researchers in this field
  • Transdisciplinary approach aims to support cross-fertilization between different sub-specialties of medicine

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Product Description:

Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin.

Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.

Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic.

  • Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic
  • Covers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field
  • Contains extensive pedagogical updates aiming to improve the education of translational researchers in this field
  • Provides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine

About the Author:

Dr Laurence is pursuing the pathophysiology of cardiovascular and skeletal abnormalities linked to HIV disease and its therapies at Weill Cornell. Dr Laurence is the editor-in-chief of Translational Medicine, which Elsevier co-publishes with the CSCTR.

The Wake Forest Institute for Regenerative Medicine was the first in the world to engineer and successfully implant an engineered organ in the lab -- bladders. As Director of the Institute, Dr. Atala oversees scientists working on therapies for more than 30 areas of the body, from heart valves and muscle tissue to livers and kidneys. Atala has received the Christopher Columbus Foundation Award, given to a living American who is currently working on a discovery that will significantly affect society. He is listed in Best Doctors in America.

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Jeffrey Laurence, Pedro Baptista, Anthony Atala
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Published by Elsevier Science Publishing Co Inc, United States (2015)
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Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 276 x 216 mm. Language: English . Brand New Book. Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. Bookseller Inventory # AA59780128005484

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Published by Elsevier Science Publishing Co Inc, United States (2015)
ISBN 10: 0128005483 ISBN 13: 9780128005484
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Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 276 x 216 mm. Language: English . Brand New Book. Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. Bookseller Inventory # AA59780128005484

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Laurence, Jeffrey
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Book Description Academic Pr, 2015. Hardcover. Book Condition: Brand New. 1st edition. 339 pages. 11.00x8.50x1.00 inches. In Stock. Bookseller Inventory # __0128005483

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Book Description Academic Press 2015-12-08, Amsterdam, 2015. hardback. Book Condition: New. Bookseller Inventory # 9780128005484

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LAURENCE, JEFFREY; BAPTISTA, PEDRO; ATALA, ANTHONY
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Book Description Academic Press, 2015. Hardback. Book Condition: NEW. 9780128005484 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE0971414

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LAURENCE, JEFFREY; BAPTISTA, PEDRO; ATALA, ANTHONY
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ISBN 10: 0128005483 ISBN 13: 9780128005484
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Book Description Academic Press, 2015. Hardback. Book Condition: NEW. 9780128005484 This listing is a new book, a title currently in-print which we order directly and immediately from the publisher. Bookseller Inventory # HTANDREE01199655

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Book Description Book Condition: New. Publisher/Verlag: Academic Press | Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin.Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic.Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinicCovers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this fieldContains extensive pedagogical updates aiming to improve the education of translational researchers in this fieldProvides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine | Introduction: Regenerative Medicine for Cardiovascular Disease-A Good StartPART I: STEM CELLS:Chapter 1: Introduction and Overview of Stem CellsChapter 2: Mechanistic Insights from Pathologic PerspectiveChapter 3: Large Animal Models to Study Stem Cell TherapySection I. Body's Native Repair MechanismsChapter 4. Evolution of understanding of the mechanisms of repairChapter 5: Impact of Age on Stem Cell FunctionSection II: Autologous Bone MarrowChapter 6: Bone Marrow Mononuclear CellsChapter 7: Chronic Limb IschemiaChapter 8: Chronic/Refractory AnginaChapter 9: Acute Myocardial InfarctionA. European Experience: Andreas ZeiherB. US Experience: Jay TraverseChapter 10: Chronic Ischemic Heart FailureSection III: Autologous Adipose Derived Regenerative CellsChapter 11: Adipose TissueSection IV: Allogeneic Alternatives to Autologous Bone MarrowChapter 12: Overview of MSCsChapter 13: Allogeneic vs Autologous Source: Comparative EffectsChapter 14: Use of MSCs for AMIChapter 15: Combined Cell StrategiesChapter 16: Heart FailureSection V: Cardiac Progenitor CellsChapter 17: C-Kit+ cellsChapter 18: CardiospheresSection VI: Other Allogeneic Sources of Stem CellsChapter 19: Umbilical Cord, Placenta, EndometriumSection VII. Genetic Engineering/Cell TransformationChapter 20: Genetic Engineering of Fibroblasts to CardiomyocytesChapter 21: Transformation to inducible Pleuripotent Stem CellsChapter 22: Transformation to MAPC'sSection VIII: METHODS OF DELIVERY:Chapter 23. Transcoronary and EndocardialChapter 24. Retrograde and EpicardialPart II. TISSUE ENGINEERING:Chapter 25. Epicardial PatchChapter 26. Matrix ScaffoldsChapter 27. Matrix plus cellsChapter 28. BiomaterialChapter 29: OrganogenesisPart III. GENE THERAPY:Chapter 30: Pre-clinical Identification of target genesChapter 31: SERCA-2a gene for recovery of inotropic functionChapter 32: SDF-1 Gene for Heart Failure Non-Inotropic MechanismsChapter 33: Gene Therapy for Angiogenesis: Chronic Limb IschemiaChapter 34: Stem Cells Target Gene Transfected Stem CellsPart IV: FUTURE DIRECTIONS:Chapter 35: CCTRN: Past, Present, and Vision for the FutureChapter 36: Signature of Responders-lessons from Bio-RepositoryChapter 37: Adjunctive therapy with LVADs for RecoveryChapter 38: Trials in Non-Ischemic Heart FailureChapter 39: Enhancing Stem Cell Homing for Tissue RepairChapter 40: Stroke: Pre-Clinical and Clinical Trial DataSUMMARY | Format: Hardba. Bookseller Inventory # K9780128005484

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Published by Elsevier Science Publishing Co Inc, United States (2015)
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Book Description Elsevier Science Publishing Co Inc, United States, 2015. Hardback. Book Condition: New. 276 x 216 mm. Language: English . This book usually ship within 10-15 business days and we will endeavor to dispatch orders quicker than this where possible. Brand New Book. Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. Bookseller Inventory # BZE9780128005484

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Jeffrey Laurence, Pedro Baptista, Anthony Atala
Published by Elsevier Science Publishing Co Inc
ISBN 10: 0128005483 ISBN 13: 9780128005484
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Book Description Elsevier Science Publishing Co Inc. Hardback. Book Condition: new. BRAND NEW, Translating Regenerative Medicine to the Clinic, Jeffrey Laurence, Pedro Baptista, Anthony Atala, Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. * Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic* Covers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field* Contains extensive pedagogical updates aiming to improve the education of translational researchers in this field* Provides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine. Bookseller Inventory # B9780128005484

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