Antibiotic Resistance: Understanding and Responding to an Emerging Crisis - Hardcover

Drlica, Karl; Perlin, David

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9780131387737: Antibiotic Resistance: Understanding and Responding to an Emerging Crisis

Hardcover

ISBN 10: 0131387731 ISBN 13: 9780131387737

Publisher: Ft Pr, 2011

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Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.

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From the Back Cover:

The emergence and spread of antibiotic resistance is a growing medical and public health emergency. Misuse and overuse of antibiotics is putting us at risk of losing our ability to cure infectious diseases. Karl Drlica and David S. Perlin give an authoritative and thorough explanation of all aspects of antibiotic resistance, from the basic science to the strategies that could minimize resistance problems and extend the life spans of existing antibiotic agents. Intended as the definitive book on a major biomedical issue, Antibiotic Resistance will be required reading for investigators and serious students in microbiology, infectious disease, pharmaceutics, and public health; physicians; and students in pharmacy, medicine, and veterinary medicine.

About the Author:

Karl Drlica, Ph.D. is a Principal Investigator at the Public Health Research Institute and Professor of Microbiology & Molecular Genetics at the UMDNJ–New Jersey Medical School in Newark. His laboratory focuses on fluoroquinolone action and resistance with Mycobacteriun tuberculosis and other bacteria, including approaches for slowing the enrichment and amplification of resistant bacterial subpopulations.

David S. Perlin, Ph.D. is Executive Director of the Public Health Research Institute and UMDNJ Regional Biocontainment Laboratory, as well as Professor of Microbiology & Molecular Genetics at the New Jersey Medical School in Newark. He is also a Fellow of the New York Academy of Sciences. Dr. Perlin’s laboratory explores mechanisms of antifungal drug-resistance, rapid detection of drug resistant bloodstream pathogens in high-risk patients, and the application of small-animal models for the study of respiratory pathogens.

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