This book serves as a reference text in the field of experimental traumatology. Chapters are written by the recognized leaders in each area. The first section covers methodological considerations, including discussion of in vitro and in vivo models; metabolic and hemodynamic factors; anatomical and electrophysiological correlates; and behavioral evaluation. The second section discusses pathophysiological factors including ischemia, ionic changes, immune-inflammatory responses, neurotransmitter/neuromodulatory alterations, effects of lipid metabolism, astroglial responses and molecular mechanisms. The final section reviews treatments including experimental pharmacology, growth factors, regeneration, transplantation and clinical treatment. This book is invaluable to researchers as well as clinicians involved in head or spinal cord injury.
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Steven K. Salzman, Chief of Spinal Trauma Program, Alfred I. DuPont Institute of the Nemours Foundation. Alan I. Faden, Professor of Neurology and Pharmacology, Georgetown University.Review:
"This is a well-written, multidisciplinary book that documents the results of extensive experience in neurotrauma. I believe clinical neurosurgeons can learn a lot about basic pathophysiology from the book. I also recommend [it] to researchers who work in this field." --M. Serdar Alp, MD,
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Book Description Oxford University Press, 1994. Hardcover. Book Condition: New. book. Bookseller Inventory # M0195072308