Type I diabetes is rapidly becoming one of the most studied autoimmune disorders. The existence of two spontaneous animal models, transgenic models which both create or suppress disease, coupled with the clinical importance of the illness with millions affected and thousands killed each year, has led to enormous efforts by an international groups of investigators to understand, treat and prevent type I diabetes.
This timely new book presents a synthesis of the molecular and cellular immunology of type I diabetes by basic immunologists and physician investigators at the Barbara Davis Center for Childhood Diabetes. At this center, T cell clones able to produce diabetes were discovered, the first antigen with which they react characterized, combinatorial, biochemical autoantibody screening for diabetes risk was recently published and multiple trials for the prevention of type I diabetes were carried out. This volume discusses the latest research in this rapidly developing field, including diagnostic strategies and therapies being developed to prevent this disease.
"synopsis" may belong to another edition of this title.
George S. Eisenbarth, Executive Director, Barbara Davis Center for Childhood Diabetes. Kevin J. Lafferty, Australia National University, Director, John Curtin School of Medical Research.Review:
"A compendium of useful information and musings covering all major aspects of the causes, natural history, and possible therapeutic approaches to autoimmune diabetes mellitus. The book hits the mark as a single-volume reference for the researcher in allied fields, the practitioner with a
specific interest, and the dedicated student. Complex issues in immunology and genetics are clearly presented, and the perspectives at the end are stimulating to further thought....A well-produced and thoughtful introduction to both the confusion and the optimism in the IDDM field circa-mid
1995."--Doody's Health Sciences Book Review
"About this title" may belong to another edition of this title.
Book Description Oxford University Press, 1996. Hardcover. Book Condition: New. book. Bookseller Inventory # M0195091264