Epistasis and the Evolutionary Process

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9780195128062: Epistasis and the Evolutionary Process
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Over the last two decades, research into epistasis has seen explosive growth and has moved the focus of research in evolutionary genetics from a traditional additive approach. We now know the effects of genes are rarely independent, and to reach a fuller understanding of the process of evolution we need to look at gene interactions as well as gene-environment interactions. This book is an overview of non-additive evolutionary genetics, integrating all work to date on all levels of evolutionary investigation of the importance of epistasis in the evolutionary process in general. It includes a historical perspective on this emerging field, in-depth discussion of terminology, discussions of the effects of epistasis at several different levels of biological organization and combinations of theoretical and experimental approaches to analysis.

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About the Author:

Jason B. Wolf is at Washington University School of Medicine.

Review:


"I learned a great deal from Epistasis and the Evolutionary Process, and I congratulate the editors on an excellent choice of authors. Graduate students and other scientists will find the book a very useful smorgasbord of recent research into theory and facts of epistasis. The volume does not attempt to resolve the 70-year-old controversy about the importance of epistasis and shifting balance. Instead, it shows that epistasis plays a central role in a much wider and more interesting variety of evolutionary problems than seemed possible even ten years ago."--Science


"This book is important because it marks the transition form a view of epistasis fixed on past controversies to a forward-looking approach where we will have a fresh look at the issues before us and embark on an exciting and significant expansion of the purview of evolutionary theory."--Evolution


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Wolf, Jason B., Brodie III, Edmund D., W
Published by Oxford University Press (2000)
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Jason B. Wolf; Edmund D. Brodie III; Michael J. Wade
Published by Oxford University Press (2000)
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