Protecting Group Chemistry (Oxford Chemistry Primers)

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9780198502753: Protecting Group Chemistry (Oxford Chemistry Primers)

Number 95 in the well-known Oxford Chemistry Primer series provides an overview of methods that allow specific sites within an organic molecule to be manipulated without affecting other sites. The book emphasizes the link between the mechanisms of organic chemistry and the choice of specific protecting groups that block chemical reactivity at those sites that must remain unaffected. The treatment differs from traditional texts in that it places the emphasis on making a connection between the fundamental mechanisms of organic chemisry - ionization, substitution, addition, elimination, oxidation, and reductionand how a particular protecting group can best be selected in a given situation.

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About the Author:

Jeremy Robertson, M.A. D.Phil., University Lecturer in Organic Chemistry and Fellow of Brasenose College, Oxford.

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"This book is another cracker from the Oxford Chemistry Primers stable that again succeeds by breaking the mould of existing books in the area". Education in Chemistry, January 2003.

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Book Description Oxford University Press, United Kingdom, 2000. Paperback. Book Condition: New. Language: English . Brand New Book. Protecting Group Chemistry provides an overview of the general methods that are used to block the reactivity of - i.e. protect - specific functional grops thus allowing others, present within the same molecule, to be manipulated unambiguously. An introductory chapter outlines protecting group strategy, relevant aspects of functional group reactivity, temporary protection, and introduces the concept of protecting group devices as an aid to unifying the wide range of available methods. The rest of the book is divided on the basis of broad classes of the experimental conditions that lead to cleavage of each protecting group (acid/electrophile, base/nucleophile, oxidising or reducing agent). The treatment differs from traditional texts in that it places the emphasis on making a connection between the fundamental mechanisms of organic chemsitry - ionisation, substitution, addition, elimination, oxidation and reduction, etc. - and how a particular protecting group can best be selected in a given situation. Bookseller Inventory # AAU9780198502753

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Book Description Oxford University Press, United Kingdom, 2000. Paperback. Book Condition: New. Language: English . Brand New Book. Protecting Group Chemistry provides an overview of the general methods that are used to block the reactivity of - i.e. protect - specific functional grops thus allowing others, present within the same molecule, to be manipulated unambiguously. An introductory chapter outlines protecting group strategy, relevant aspects of functional group reactivity, temporary protection, and introduces the concept of protecting group devices as an aid to unifying the wide range of available methods. The rest of the book is divided on the basis of broad classes of the experimental conditions that lead to cleavage of each protecting group (acid/electrophile, base/nucleophile, oxidising or reducing agent). The treatment differs from traditional texts in that it places the emphasis on making a connection between the fundamental mechanisms of organic chemsitry - ionisation, substitution, addition, elimination, oxidation and reduction, etc. - and how a particular protecting group can best be selected in a given situation. Bookseller Inventory # AAU9780198502753

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